DRSC/TRiP Functional Genomics Resources

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Protein Alignment gbb and Inhba

DIOPT Version :9

Sequence 1:NP_001286786.1 Gene:gbb / 37778 FlyBaseID:FBgn0024234 Length:455 Species:Drosophila melanogaster
Sequence 2:NP_058824.1 Gene:Inhba / 29200 RGDID:62074 Length:424 Species:Rattus norvegicus


Alignment Length:445 Identity:106/445 - (23%)
Similarity:173/445 - (38%) Gaps:133/445 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 VSYEILEFLGIAERPTHLSSHQLSLRKSAPK-FLLDVYHRI-TAEEGLSDQDEDDDYERGHRSRR 126
            |...||..|.:.:||        .:.:..|| .||:...:: ..:.|          |.|:    
  Rat    58 VKKHILNMLHLKKRP--------DVTQPVPKAALLNAIRKLHVGKVG----------ENGY---- 100

  Fly   127 SADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHG---RRLWFDVSNVPND 188
             .::|:|.|.:.:  :.:|    ::::..|:||.            |.|   :.|.|::|...:|
  Rat   101 -VEIEDDIGRRAE--MNEL----MEQTSEIITFA------------ESGTARKTLHFEISKEGSD 146

  Fly   189 NYLVMAELRIYQNANEGKWL-----TANR---EFTITVY---------------AIGTGTLGQHT 230
                   |.:.:.|.  .||     .|||   :.||.::               |...|..|:.:
  Rat   147 -------LSVVERAE--VWLFLKVPKANRTRTKVTIRLFQQQKHPQGSLDMGDEAEEMGLKGERS 202

  Fly   231 MEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYI--------GAHAV---NRPDREVKL 284
            ...||..........|....|:..:...|.:.|.:..:.|        ||..|   .:..:||..
  Rat   203 ELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEVDG 267

  Fly   285 D-------DIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNV 342
            |       |.||...| :...:||::                 .::::|..||.:|::..     
  Rat   268 DGKKKDGSDGGLEEEK-EQSHRPFLM-----------------LQARQSEDHPHRRRRRG----- 309

  Fly   343 PLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGEC--------NFPLNAHMNATN 399
              ||.......|..:..::.|||:||:||||||.||.|.||.|||        ...|:.|....|
  Rat   310 --LECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVIN 372

  Fly   400 HAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            |..::.  |  .|....|.||.||:|..:.:||:.:.:|:..|..:||||:.|||
  Rat   373 HYRMRG--H--SPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGC 423

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
gbbNP_001286786.1 TGFb_propeptide 44..305 CDD:279078 57/286 (20%)
TGFB 354..455 CDD:214556 43/109 (39%)
InhbaNP_058824.1 TGFb_propeptide 56..236 CDD:413528 43/227 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 264..306 12/59 (20%)
TGF_beta_INHBA 317..424 CDD:381674 43/111 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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