Protein Alignment gbb and Inhbb

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_542949.1
• Gene: Inhbb / 25196
• RGDID: 2913
• Length: 411
• Species: Rattus norvegicus
• Alignment Length: 301
• Identity: 82/301 - (27%)
• Similarity: 128/301 - (42%)
• Gaps: 75/301 - (24%)

  Fly   177 RLWFDVSNVPNDN-YLVMAELRIYQN-----ANEGKWLTANREFTITVYAIGTGTLGQ-HTMEPL 234
            ||:|.|||..|.| ::|.|.|.:|..     ..:|    :.|:..:.||....|...: :.:|..
  Rat   162 RLYFFVSNEGNQNLFVVQASLWLYLKLLPYVLEKG----SRRKVRVKVYFQEQGHGDRWNVVEKK 222

  Fly   235 SSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLD-------DIGLIHR 292
            ..:..:    ||....:||.:..                ...|.:|.:.||       ::.::..
  Rat   223 VDLKRS----GWHTFPITEAIQA----------------LFERGERRLNLDVQCDSCQELAVVPV 267

  Fly   293 KVD---DEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSC 354
            .||   :..:||::        ::|....|.||.       |||.          ||....|..|
  Rat   268 FVDPGEESHRPFVV--------VQARLGDSRHRI-------RKRG----------LECDGRTSLC 307

  Fly   355 QMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGEC-----NFPLNAHMNATNHAIV-QTLVHLLEPK 413
            ..|..:|||:.:||:||||||.||...||.|.|     ..|.:|  ::.:.|:| |..:..|.|.
  Rat   308 CRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSA--SSFHTAVVNQYRMRGLNPG 370

  Fly   414 KVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .| ..||.||:|.::.:||..::.|:..:...||||:.|||
  Rat   371 PV-NSCCIPTKLSSMSMLYFDDEYNIVKRDVPNMIVEECGC 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	30/144 (21%)
		TGF_beta_BMP5_like	353..455	CDD:381639	42/108 (39%)
Inhbb	NP_542949.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..69
		TGFb_propeptide	73..282	CDD:480997	30/151 (20%)
		TGF_beta_INHBB	305..411	CDD:381675	42/109 (39%)