Protein Alignment gbb and Gdf7

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001299805.1
• Gene: Gdf7 / 238057
• MGIID: 95690
• Length: 461
• Species: Mus musculus
• Alignment Length: 378
• Identity: 91/378 - (24%)
• Similarity: 139/378 - (36%)
• Gaps: 142/378 - (37%)

  Fly   173 EHGRRLWFDVSNVPNDNYLVMAELRIYQNAN---EGKWLTANREFTITVYAIGTGT---LGQHTM 231
            |.|:...||||::...:.:|.||||:.:..:   :....|......::......||   |.....
Mouse   129 EPGQSFLFDVSSLSEADEVVNAELRVLRRRSPEPDRDSATLLPRLLLSTCPDEAGTAHLLHSRAA 193

  Fly   232 EPLSSVNTTGDYVGWLELNVTEGL---HEWLVKSK------------------------------ 263
            |||....       |...:||:.:   ..|...|:
Mouse   194 EPLGGAR-------WEAFDVTDAVQSHRRWPRASRKFCLVLRAVTASESSPLALRRLGFGWPGGG 251

  Fly   264 DNHGIYIGAHAV----NRPDREVKLDDIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSK 324
            |..|......|:    :|..|:..|                     ||.   |:|.|     |:.
Mouse   252 DGGGTAAEERALLVISSRTQRKESL---------------------FRE---IRAQA-----RAL 287

  Fly   325 RSASHP-----------------RKRKKSVSPNNVPLLEPMESTRS------------------- 353
            |:|:.|                 |:|:::.          :..||.
Mouse   288 RAAAEPPPDPGPGAGSRKANLGGRRRRRTA----------LAGTRGAQGSGGGGGGGGGGGGGGG 342

  Fly   354 -----------------CQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHA 401
                             |..::|::|||:|||.||||||..|.|::|.|.|:|||.:|:..||||
Mouse   343 GGGGGAGRGHGRRGRSRCSRKSLHVDFKELGWDDWIIAPLDYEAYHCEGVCDFPLRSHLEPTNHA 407

  Fly   402 IVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            |:|||::.:.|...|..||.|.||..:.:||.....||..|:|.:|:|::|||
Mouse   408 IIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	29/174 (17%)
		TGFB	354..455	CDD:214556	49/101 (49%)
Gdf7	NP_001299805.1	TGFb_propeptide	<87..232	CDD:279078	23/109 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..360		7/82 (9%)
		TGFB	363..461	CDD:214556	48/98 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810