Protein Alignment gbb and Tgfb2

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001316036.1
• Gene: Tgfb2 / 21808
• MGIID: 98726
• Length: 442
• Species: Mus musculus
• Alignment Length: 316
• Identity: 87/316 - (27%)
• Similarity: 133/316 - (42%)
• Gaps: 75/316 - (23%)

  Fly   180 FDVSNV-PNDNYLVMAELRIYQNANEGKWLTANREFTITVYAI-GTGTLGQHTMEPLSS--VNTT 240
            ||||.: .|.:.||.||.|:::..|....:...|   |.:|.| .:..|...|...:.|  |.|.
Mouse   160 FDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQR---IELYQILKSKDLTSPTQRYIDSKVVKTR 221

  Fly   241 GDYVG-WLELNVTEGLHEWLVKSKDNHGIYIGAHA------------VNRPDREVKLDDIGLIHR 292
            .:  | ||..:||:.:.|||.....|.|..|..|.            :.....|::....|:
Mouse   222 AE--GEWLSFDVTDAVQEWLHHKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGI--- 281

  Fly   293 KVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKKSVSPNNVPLLEP---MESTRS- 353
               |....:..|   ..:.||:|               ||:....:|:.:.:|.|   :||.:|
Mouse   282 ---DGTSTYASG---DQKTIKST---------------RKKTSGKTPHLLLMLLPSYRLESQQSS 325

  Fly   354 -------------------CQMQTLYIDFK-DLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNAT 398
                               |.::.|||||| |||| .||..|:||.|.:|:|.|.:..::.   |
Mouse   326 RRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW-KWIHEPKGYNANFCAGACPYLWSSD---T 386

  Fly   399 NHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .|..|.:|.:.:.|:....|||....|..|.:||::.: ...:::..|||||||.|
Mouse   387 QHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIGN-TPKIEQLSNMIVKSCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	35/141 (25%)
		TGFB	354..455	CDD:214556	40/102 (39%)
Tgfb2	NP_001316036.1	TGFb_propeptide	21..256	CDD:279078	32/100 (32%)
		TGF_beta	344..441	CDD:278448	39/101 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810