Protein Alignment gbb and Nodal

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_038639.2
• Gene: Nodal / 18119
• MGIID: 97359
• Length: 354
• Species: Mus musculus
• Alignment Length: 358
• Identity: 85/358 - (23%)
• Similarity: 136/358 - (37%)
• Gaps: 115/358 - (32%)

  Fly   148 RAIDESDIIMTFLNKRHHNVDELRHEHGRRLW---FDVSNVPNDNYLVMAELRI-----YQNANE 204
            |::...|:.:|..|                 |   ||.|.:..:..||.||||:     .....|
Mouse    60 RSLQAQDVDVTGQN-----------------WTFTFDFSFLSQEEDLVWAELRLQLPGPMDIPTE 107

  Fly   205 GKWLTANREFTITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLE-----------------LNVT 252
            |       ..||.::....|...:...:.|..:        |:|                 |.||
Mouse   108 G-------PLTIDIFHQAKGDPERDPADCLERI--------WMETFTVIPSQVTFASGSTVLEVT 157

  Fly   253 EGLHEWL---------VKSKDN---HGIYIGAHAV----------NRPDREVKLDDIGLIHRKVD 295
            :.|.:||         |.|:..   |..|.....|          |||..:.:|....|:..
Mouse   158 KPLSKWLKDPRALEKQVSSRAEKCWHQPYTPPVPVASTNVLMLYSNRPQEQRQLGGATLLWE--- 219

  Fly   296 DEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPR----KRKKSVSPNNVPLLEPMESTRSCQM 356
                                |.||....:...|..|    :|::.   :::|     :.::.|:.
Mouse   220 --------------------AESSWRAQEGQLSVERGGWGRRQRR---HHLP-----DRSQLCRR 256

  Fly   357 QTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCA 421
            ....:||..:||..|||.|:.|.|:.|.|||..|:....:.||||.:|:|:...:|.:||..|||
Mouse   257 VKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCA 321

  Fly   422 PTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            |.:...|.:|| :::..|.|:.:::|||:.|||
Mouse   322 PVKTKPLSMLY-VDNGRVLLEHHKDMIVEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	38/203 (19%)
		TGFB	354..455	CDD:214556	40/101 (40%)
Nodal	NP_038639.2	TGFb_propeptide	33..169	CDD:279078	28/140 (20%)
		TGFB	254..353	CDD:214556	38/99 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810