Protein Alignment gbb and unc-129

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_501566.1
• Gene: unc-129 / 177719
• WormBaseID: WBGene00006852
• Length: 407
• Species: Caenorhabditis elegans
• Alignment Length: 461
• Identity: 96/461 - (20%)
• Similarity: 166/461 - (36%)
• Gaps: 141/461 - (30%)

  Fly    61 KLDVSY------EILEFLGIAERPT--HLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDD 117
            |:||..      ::|.|.......|  |.|||.|:      :.:.::|      |...|:|.::|
 Worm    20 KVDVDLINETIRDLLHFKSSDPNVTSFHRSSHTLT------EHMKNLY------ENFIDEDSNED 72

  Fly   118 YERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIM------------TFLNKRHHNV--- 167
               |:..|.   :|...|:.:...:...|....|..:.||            :|..:|...:
 Worm    73 ---GNLVRA---IEPAVGKFEGQEVLVFDVEGFDSHESIMRAELHFYLRRRDSFARRRSRQIRAK 131

  Fly   168 --------------------DELRHEHGRRLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANR 212
                                ||...|: :.:| |.:....|:|.:.|:..:::...|...:....
 Worm   132 SVCVNEYCRQQTLKKIRVGGDENLEEY-KVIW-DATKSVFDSYHLDAKQAVFRITREHSKMRPYA 194

  Fly   213 EFT------ITVYAIGTGTLGQHTMEPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKD--NHGI- 268
            |..      :.:|               |.||.|.|.|     :|.:...:...|.:|  |..:
 Worm   195 EMIRKSTPFLVIY---------------SKVNHTLDTV-----SVMKQTEQTKRKRRDLGNEELR 239

  Fly   269 -YIGAHAV--NRPDREVKLDDIGLIHRK------------VDDEFQPFMIGFFRGPELIKATAHS 318
             |...:::  :..|||.       |.||            .:|.:|.|      |.|       :
 Worm   240 EYYNYNSIPLDNDDREP-------IKRKNGKKNSLSEEISSEDVWQGF------GEE-------T 284

  Fly   319 SHHRSKRSASHPRKRKKSVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYC 383
            |....:|.|:     ::..:...|.||   ::...|..:.:.:..|..||..::|.|:.....:|
 Worm   285 SREERERIAN-----EELANDVRVVLL---QNKNRCHKEGVLVSLKHFGWDRYVIEPKTIETSFC 341

  Fly   384 SGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMI 448
            .|:|..|:.....|:|||::|:| ...||     .|||||.|.:|...|........::.|..|:
 Worm   342 KGKCAKPMLTSGKASNHAMLQSL-FAAEP-----VCCAPTNLKSLNFWYRDEKGRTVIRNYSKML 400

  Fly   449 VKSCGC 454
            :.||.|
 Worm   401 IGSCSC 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	57/310 (18%)
		TGFB	354..455	CDD:214556	31/101 (31%)
unc-129	NP_501566.1	TGFB	312..406	CDD:214556	30/99 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810