Protein Alignment gbb and Inhba

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_032406.1
• Gene: Inhba / 16323
• MGIID: 96570
• Length: 424
• Species: Mus musculus
• Alignment Length: 452
• Identity: 108/452 - (23%)
• Similarity: 174/452 - (38%)
• Gaps: 147/452 - (32%)

  Fly    64 VSYEILEFLGIAERPTHLSSHQLSLRKSAPK-FLLDVYHRI-TAEEGLSDQDEDDDYERGHRSRR 126
            |...||..|.:.:||        .:.:..|| .||:...:: ..:.|          |.|:
Mouse    58 VKKHILNMLHLKKRP--------DVTQPVPKAALLNAIRKLHVGKVG----------ENGY---- 100

  Fly   127 SADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRHHNVDELRHEHG---RRLWFDVSNVPND 188
             .::|:|.|.:.:  :.:|    ::::..|:||.            |.|   :.|.|::|...:|
Mouse   101 -VEIEDDIGRRAE--MNEL----MEQTSEIITFA------------ESGTARKTLHFEISKEGSD 146

  Fly   189 NYLVMAELRIYQNANEGKWL-----TANREFT-ITVYAIGTGTLGQHTMEPLSSVNTTGDYV--- 244
                   |.:.:.|.  .||     .|||..| :|:      .|.|....|..|:: |||..
Mouse   147 -------LSVVERAE--VWLFLKVPKANRTRTKVTI------RLFQQQKHPQGSLD-TGDEAEEM 195

  Fly   245 ---------------------GWLELNVTEGLHEWLVKSKDNHGIYI--------GAHAV---NR 277
                                 .|....|:..:...|.:.|.:..:.|        ||..|   .:
Mouse   196 GLKGERSELLLSEKVVDARKSTWHIFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKK 260

  Fly   278 PDREVKLD-------DIGLIHRKVDDEFQPFMIGFFRGPELIKATAHSSHHRSKRSASHPRKRKK 335
            ..:||..|       |.||...| :...:||::                 .::::|..||.:|::
Mouse   261 KKKEVDGDGKKKDGSDGGLEEEK-EQSHRPFLM-----------------LQARQSEDHPHRRRR 307

  Fly   336 SVSPNNVPLLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGEC--------NFPLN 392
            ..       ||.......|..:..::.|||:||:||||||.||.|.||.|||        ...|:
Mouse   308 RG-------LECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLS 365

  Fly   393 AHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .|....||..::.  |  .|....|.||.||:|..:.:||:.:.:|:..|..:||||:.|||
Mouse   366 FHSTVINHYRMRG--H--SPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGC 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	59/293 (20%)
		TGFB	354..455	CDD:214556	43/109 (39%)
Inhba	NP_032406.1	TGFb_propeptide	56..291	CDD:366248	58/290 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		12/59 (20%)
		TGF_beta_INHBA	317..424	CDD:381674	43/111 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810