Protein Alignment gbb and Lefty1

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_034224.1
• Gene: Lefty1 / 13590
• MGIID: 107405
• Length: 368
• Species: Mus musculus
• Alignment Length: 376
• Identity: 73/376 - (19%)
• Similarity: 129/376 - (34%)
• Gaps: 129/376 - (34%)

  Fly   145 LDKRAIDESDIIMTFLNKRHHNVDELRHEH-----------------GRRLWFDVS--------- 183
            |||..: |..:|.:.:..::  |..|:|.|                 ||.|..:.|
Mouse    43 LDKADV-EGMVIPSHVRTQY--VALLQHSHASRSRGKRFSQNLREVAGRFLVSETSTHLLVFGME 104

  Fly   184 -NVPNDNYLVMAELRIYQNANEGKWLTANREFT-------ITVYAIGTGTLGQHTMEPLSSVNTT 240
             .:|.::.||.|.||::|.......|...:..:       :|:..:.....|.:....:.|...:
Mouse   105 QRLPPNSELVQAVLRLFQEPVPRTALRRQKRLSPHSARARVTIEWLRFRDDGSNRTALIDSRLVS 169

  Fly   241 GDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDDEFQPFMIGF 305
            ....||...:|||.::.|              ..::||
Mouse   170 IHESGWKAFDVTEAVNFW--------------QQLSRP--------------------------- 193

  Fly   306 FRGPELIKATAHSSH--------HRSKRSAS----------------HPRKRKKSVSPNNVPLLE 346
             |.|.|::.:....|        |:..|.|:                |....|...:..|.....
Mouse   194 -RQPLLLQVSVQREHLGPGTWSSHKLVRFAAQGTPDGKGQGEPQLELHTLDLKDYGAQGNCDPEA 257

  Fly   347 PM-ESTRSCQMQTLYIDFKDLGW-HDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHL 409
            |: |.||.|: |.:|:|.:.:.| .:||:.|.|:..:.|.|.|   |....:.|:.
Mouse   258 PVTEGTRCCR-QEMYLDLQGMKWAENWILEPPGFLTYECVGSC---LQLPESLTSR--------- 309

  Fly   410 LEPKKVPKPCCAPTRLGALPVLYHLND------ENVNLKKYRNMIVKSCGC 454
             .|...|:.|.| :.:.:||::..:.:      :.|:|.   ||.|::|.|
Mouse   310 -WPFLGPRQCVA-SEMTSLPMIVSVKEGGRTRPQVVSLP---NMRVQTCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	32/193 (17%)
		TGFB	354..455	CDD:214556	27/108 (25%)
Lefty1	NP_034224.1	TGFb_propeptide	<106..211	CDD:279078	23/146 (16%)
		TGF_beta	263..355	CDD:278448	28/109 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810