Protein Alignment gbb and Bmp8a

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001242948.1
• Gene: Bmp8a / 12163
• MGIID: 104515
• Length: 412
• Species: Mus musculus
• Alignment Length: 441
• Identity: 142/441 - (32%)
• Similarity: 215/441 - (48%)
• Gaps: 92/441 - (20%)

  Fly    50 TIMHRVLSEDDKLDVSYEILEFLGIAERPTHLSSHQLSLR-KSAPKFLLDVYHRITAEEGLSDQD 113
            |...|.|...::.|:..|||..||:..||...:....:.: .|||.|:||:||.:|
Mouse    29 TCPQRRLGARERRDMQREILAVLGLPGRPRPRAQPAAARQPASAPLFMLDLYHAMT--------- 84

  Fly   114 EDDDYERGHRSRRSADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLN--KRHHNVDELRHEHGR 176
             |||               |.|..|.:         :..:|::|:|:|  :|...:. .:..|.:
Mouse    85 -DDD---------------DGGPPQAH---------LGRADLVMSFVNMVERDRTLG-YQEPHWK 123

  Fly   177 RLWFDVSNVPNDNYLVMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHT----------M 231
            ...||::.:|....:..||.|||:   |......|....|:::.:    :.:|:          :
Mouse   124 EFHFDLTQIPAGEAVTAAEFRIYK---EPSTHPLNTTLHISMFEV----VQEHSNRESDLFFLDL 181

  Fly   232 EPLSSVNTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYIGAHAVNRPDREVKLDDIGLIHRKVDD 296
            :.|.|    || .|||.|::|.....||:....:.|:.:.....:....:..|  .||:.|:...
Mouse   182 QTLRS----GD-EGWLVLDITAASDRWLLNHHKDLGLRLYVETADGHSMDPGL--AGLLGRQAPR 239

  Fly   297 EFQPFMIGFFRGPELIKATAHSSHHRSKRSA-----SHPRKRKKSVSPNNVP-LLEPMESTRS-- 353
            ..||||:.|||        |..|..|:.|:|     ..|:|..:...||.:| :.:....:|.
Mouse   240 SRQPFMVTFFR--------ASQSPVRAPRAARPLKRRQPKKTNELPHPNKLPGIFDDGHGSRGRE 296

  Fly   354 -CQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTL----------- 406
             |:...||:.|:||||.||:|||:||.|:||.|||.|||::.||||||||:|:|
Mouse   297 VCRRHELYVSFRDLGWLDWVIAPQGYSAYYCEGECAFPLDSCMNATNHAILQSLVSTTVACCDRW 361

  Fly   407 --VHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGCH 455
              |||::|..|||.|||||:|.|..|||:.:..||.|:|:|||:||:||||
Mouse   362 SGVHLMKPDVVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	64/267 (24%)
		TGFB	354..455	CDD:214556	62/113 (55%)
Bmp8a	NP_001242948.1	TGFb_propeptide	32..248	CDD:279078	63/264 (24%)
		TGF_beta	298..411	CDD:278448	61/112 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3704
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	260	1.000	Inparanoid score	I3096
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47130
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	1	1.000	-	-		otm44064
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.940