Protein Alignment gbb and Bmp4

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001303289.1
• Gene: Bmp4 / 12159
• MGIID: 88180
• Length: 408
• Species: Mus musculus
• Alignment Length: 436
• Identity: 116/436 - (26%)
• Similarity: 185/436 - (42%)
• Gaps: 128/436 - (29%)

  Fly    63 DVSYEILEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRS 127
            |....:|:..|:..||      |.|.....|.::.|:|                         |.
Mouse    56 DFEATLLQMFGLRRRP------QPSKSAVIPDYMRDLY-------------------------RL 89

  Fly   128 ADLEEDEGEQQKNFITDLDKRAIDESDIIMTFLNKRH-HNVDELRHEHGRRLWFDVSNVPNDNYL 191
            ...||:|.||.:....:..:|....::.:.:|.::.| .|:.........|..|::|::|.:..:
Mouse    90 QSGEEEEEEQSQGTGLEYPERPASRANTVRSFHHEEHLENIPGTSESSAFRFLFNLSSIPENEVI 154

  Fly   192 VMAELRIY-QNANEG-KWLTANREF-TITVYAIGTGTLGQHTMEPLSSV---------------- 237
            ..||||:: :..::| .|   .:.| .|.:|.:         |:|.:.:
Mouse   155 SSAELRLFREQVDQGPDW---EQGFHRINIYEV---------MKPPAEMVPGHLITRLLDTRLVH 207

  Fly   238 -NTTGDYVGWLELNVTEGLHEWLVKSKDNHGIYI------------GAHAVNRPDREVKLDDIGL 289
             |.|    .|...:|:..:..|..:.:.|:|:.|            |.|.              .
Mouse   208 HNVT----RWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHV--------------R 254

  Fly   290 IHRKVDD------EFQPFMIGF---FRGPELIKATAHSSHHRSKRSASH--PRKRKKSVSPNNVP 343
            |.|.:..      :.:|.::.|   .||..|       :..|:|||..|  .|.|||:
Mouse   255 ISRSLPQGSGDWAQLRPLLVTFGHDGRGHTL-------TRRRAKRSPKHHPQRSRKKN------- 305

  Fly   344 LLEPMESTRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVH 408
                    ::|:..:||:||.|:||:|||:||.||.||||.|:|.|||..|:|:||||||||||:
Mouse   306 --------KNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVN 362

  Fly   409 LLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            .:. ..:||.||.||.|.|:.:||....:.|.||.|:.|:|:.|||
Mouse   363 SVN-SSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	48/280 (17%)
		TGFB	354..455	CDD:214556	55/101 (54%)
Bmp4	NP_001303289.1	TGFb_propeptide	41..276	CDD:279078	48/280 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..111		5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307		12/47 (26%)
		TGFB	308..408	CDD:214556	55/101 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810