Protein Alignment gbb and gdf9

DIOPT Version :10

• Sequence 1: NP_477340.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_002935305.1
• Gene: gdf9 / 100496740
• XenbaseID: XB-GENE-478149
• Length: 421
• Species: Xenopus tropicalis
• Alignment Length: 243
• Identity: 56/243 - (23%)
• Similarity: 98/243 - (40%)
• Gaps: 36/243 - (14%)

  Fly   246 WLELNVTEGLHEWLVKSKDNHGIYIGAH------------AVNRPDREVK--------LDDIG-- 288
            |:|::||..|..::...:.|  |::|.:            |...|.:..:        |:|..
 Frog   180 WVEIDVTSILQPFISNKRQN--IHLGLNFTCMKNNKHYDFATTGPFKMTRSPPSLLLYLNDTSNK 242

  Fly   289 LIHRKV--DDEFQPFMIGFFRGPELIKATAHS--SHHRSKRSASHP----RKRKKSVSPNNVPLL 345
            ..||::  |...||......|.|.::.....:  ....|:|..:|.    .:...:|.|:.....
 Frog   243 AYHRRIMHDIAEQPLYYPVGRIPSILADDEGNLKLQQMSRRRRNHDYEAILEENTTVVPHTFNFS 307

  Fly   346 EPME----STRSCQMQTLYIDFKDLGWHDWIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTL 406
            |.::    |...|::....:.|..|.|..||:||..|...||.|.|...:.....:..|.|||.:
 Frog   308 EYLKQFVYSHNECELHRFRLSFSQLNWDKWILAPHRYSPDYCKGVCPRIVGHRYGSPVHTIVQNI 372

  Fly   407 VHLLEPKKVPKPCCAPTRLGALPVLYHLNDENVNLKKYRNMIVKSCGC 454
            ::......:|:|.|.|:....:.||....|.::..|:|::||...|.|
 Frog   373 IYEKVDSSIPRPSCVPSEYRPMSVLTIEPDNSIAYKEYQDMIATKCTC 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_477340.1	TGFb_propeptide	45..305	CDD:459906	17/82 (21%)
		TGF_beta_BMP5_like	353..455	CDD:381639	30/102 (29%)
gdf9	XP_002935305.1	TGF_beta_GDF9	318..421	CDD:381673	30/103 (29%)