Protein Alignment gbb and bmp8

DIOPT Version :9

• Sequence 1: NP_001286786.1
• Gene: gbb / 37778
• FlyBaseID: FBgn0024234
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: XP_002941697.3
• Gene: bmp8 / 100494880
• XenbaseID: XB-GENE-485424
• Length: 425
• Species: Xenopus tropicalis
• Alignment Length: 475
• Identity: 163/475 - (34%)
• Similarity: 247/475 - (52%)
• Gaps: 83/475 - (17%)

  Fly     4 LRNTSEAVAVLASLGLGMVLLMFVATTPPAVEATQSGIYIDNGKDQTIMHRVLSEDDKLDVSYEI 68
            |:.|..|:::||.|.                :.| ||.::.|....:.:.|.||..:|.::..||
 Frog    11 LQMTLAAMSILAILW----------------DLT-SGSFVKNHLHSSFIQRKLSGREKREMQREI 58

  Fly    69 LEFLGIAERPTHLSSHQLSLRKSAPKFLLDVYHRITAEEGLSDQDEDDDYERGHRSRRSADLEED 133
            |..:|:..||...|...:.  .|||.|:||:||.:.:||   |:|......|.|
 Frog    59 LSIMGLPGRPRPASGGHVP--SSAPLFMLDLYHAMCSEE---DEDGMPGVSRAH----------- 107

  Fly   134 EGEQQKNFITDLDKRA------IDESDIIMTFLNKRHHNVDELRHE-HGRRLWFDVSNVPNDNYL 191
                    .|.|..::      |.|:|.:|:|:|...|:.|..:.: :.:...||::.:|....:
 Frog   108 --------FTTLSTQSPPLGTVISEADTVMSFVNMVEHDRDIFQQKPYWKEFKFDMTQIPTGESV 164

  Fly   192 VMAELRIYQNANEGKWLTANREFTITVYAIGTGTLGQHTMEP----LSSVNTTGDYVGWLELNVT 252
            .:||.|:::..:..:.|  ||...|:::.|   ...:...||    |...:|.....|||..:||
 Frog   165 TVAEFRLFKMRSFLRNL--NRTLHISLFEI---KKERGHREPELTLLDHESTLAGDEGWLVFDVT 224

  Fly   253 EGLHEWLVKSKDNHGI--YIGAHAVNRPDREVKLDD--IGLIHRKVDDEFQPFMIGFFRGPELIK 313
            ...:.||:.||:|.||  |:      ..|:...:|.  .|::.|:.....||||:.|||
 Frog   225 AASNHWLLNSKNNLGIRLYV------ETDQGQSIDPGIAGILGRRAPRSKQPFMVTFFR------ 277

  Fly   314 ATAHSSHHRSKRSASHPRKRKKS----VSPNNVP-LLEPMESTRS---CQMQTLYIDFKDLGWHD 370
              ...:..||.|:....|||::.    ..||.:| :|:.:..|.|   |:...||:.|:||||.|
 Frog   278 --VSRNQIRSARAVKQLRKRQQKKHDLPHPNKLPGILDHLHVTDSRQVCKRHELYVSFRDLGWLD 340

  Fly   371 WIIAPEGYGAFYCSGECNFPLNAHMNATNHAIVQTLVHLLEPKKVPKPCCAPTRLGALPVLYHLN 435
            |:|||:||.||||.|||:|||::.||||||||:|:||||::|:.|||.|||||:|.|..|||:.:
 Frog   341 WVIAPQGYSAFYCEGECSFPLDSCMNATNHAILQSLVHLMKPESVPKACCAPTKLSATSVLYYDS 405

  Fly   436 DENVNLKKYRNMIVKSCGCH 455
            :.||.|||:|||:|||||||
 Frog   406 NNNVILKKHRNMVVKSCGCH 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gbb	NP_001286786.1	TGFb_propeptide	44..305	CDD:279078	72/275 (26%)
		TGFB	354..455	CDD:214556	65/100 (65%)
bmp8	XP_002941697.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	172	1.000	Domainoid score	I3678
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	259	1.000	Inparanoid score	I3042
OMA	1	1.010	-	-		QHG47130
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	1	1.000	-	-		otm49237
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.080