Protein Alignment CG5554 and TMX1

DIOPT Version :9

• Sequence 1: NP_001286784.1
• Gene: CG5554 / 37775
• FlyBaseID: FBgn0034914
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_110382.3
• Gene: TMX1 / 81542
• HGNCID: 15487
• Length: 280
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 110/267 - (41%)
• Similarity: 163/267 - (61%)
• Gaps: 14/267 - (5%)

  Fly     8 VAATCAALLLLAATAQSTAAAQSGLQPGGKLIELDEDNWHLMLQGEWMIEFFAPWCPACKNLAPT 72
            :|...|.|:||...|..|...:|.::      .:.::||..:|:|:|||||:|||||||:||.|.
Human     7 LAVPLAVLVLLLWGAPWTHGRRSNVR------VITDENWRELLEGDWMIEFYAPWCPACQNLQPE 65

  Fly    73 WERFARVAKDVQVQVAKIDVTTSPSLSGRFFVTALPTIYHVKDGEFRQYRGARDGDALLYFVKKQ 137
            ||.||...:|::|.:||:|||..|.|||||.:||||||||.||||||:|:|.|.....:.|:..:
Human    66 WESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDK 130

  Fly   138 QWQSIEPLSAWKKPDTTHMSVLSYFFKLSHTLKHTQKLFKDFNGRLQEEYGLPTWGSYALFAIAT 202
            :|:||||:|:|..|.:..||.:|..|:||..::.....|       .|:.|||.||||.:||:||
Human   131 EWKSIEPVSSWFGPGSVLMSSMSALFQLSMWIRTCHNYF-------IEDLGLPVWGSYTVFALAT 188

  Fly   203 IFVGAALGLLLVCLVDFVYPPKKSQRQSFS-ESQDNLTEGLEDLATEEIEDDGDAEENDDEQRDS 266
            :|.|..|||.::.:.|.:.|.|:.:.|.:. .|:..|:|..:.|...|.|.:.|.|:..:|:.:|
Human   189 LFSGLLLGLCMIFVADCLCPSKRRRPQPYPYPSKKLLSESAQPLKKVEEEQEADEEDVSEEEAES 253

  Fly   267 DEEEQED 273
            .|...:|
Human   254 KEGTNKD 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5554	NP_001286784.1	PDI_a_TMX	36..136	CDD:239292	54/99 (55%)
TMX1	NP_110382.3	PDI_a_TMX	29..129	CDD:239292	55/105 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	218..280		12/43 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5084
eggNOG	1	0.900	-	-		E2759_KOG0913
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12482
Inparanoid	1	1.050	218	1.000	Inparanoid score	I3592
Isobase	1	0.950	-	0	Normalized mean entropy	S2346
OMA	1	1.010	-	-		QHG47726
OrthoDB	1	1.010	-	-		D1481386at2759
OrthoFinder	1	1.000	-	-		FOG0006167
OrthoInspector	1	1.000	-	-		otm41981
orthoMCL	1	0.900	-	-		OOG6_106530
Panther	1	1.100	-	-	LDO	PTHR46107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3134
SonicParanoid	1	1.000	-	-		X5609
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.820