Protein Alignment CG5554 and Pdia5

DIOPT Version :10

• Sequence 1: NP_001286784.1
• Gene: CG5554 / 37775
• FlyBaseID: FBgn0034914
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_082571.1
• Gene: Pdia5 / 72599
• MGIID: 1919849
• Length: 517
• Species: Mus musculus
• Alignment Length: 170
• Identity: 45/170 - (26%)
• Similarity: 79/170 - (46%)
• Gaps: 33/170 - (19%)

  Fly    35 GGKLIELDEDNWHLMLQ--GEWMIEFFAPWCPACKNLAPTWERFARVAK-DVQVQ--VAKIDVTT 94
            ||.:..|.::::...::  ...::.|.||||..||.:.|.:|..|.|.. |.:..  :|.:|.|.
Mouse   273 GGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFESAAEVLHGDAESSGVLAAVDATV 337

  Fly    95 SPSLSGRFFVTALPTIYHVKDGEFRQYRGARDGDALLYFVKKQ--QW-QSIE----PLSAWKKPD 152
            :.:|:|||.::|.||:.:.|:||.:.....|        .||:  :| |:.|    |...|::..
Mouse   338 NEALAGRFHISAFPTLKYFKNGEQQAVPALR--------TKKKFIEWMQNPEAPPPPEPTWEEQQ 394

  Fly   153 TTHMSVLSYFF-----KLSHTL--------KHTQKLFKDF 179
            |:.:.::...|     |..|||        .|.:|:...|
Mouse   395 TSVLHLVGDNFRDTLKKKKHTLVMFYAPWCPHCKKVIPHF 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5554	NP_001286784.1	PDI_a_TMX	36..136	CDD:239292	28/104 (27%)
Pdia5	NP_082571.1	PDI_b_PDIR_N	26..137	CDD:239365
		PDI_a_PDIR	150..254	CDD:239295
		PDI_a_PDIR	275..377	CDD:239295	29/109 (27%)
		PDI_a_PDIR	396..499	CDD:239295	8/39 (21%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	514..517