Protein Alignment CG5554 and TMX4

DIOPT Version :9

• Sequence 1: NP_001286784.1
• Gene: CG5554 / 37775
• FlyBaseID: FBgn0034914
• Length: 330
• Species: Drosophila melanogaster
• Sequence 2: NP_066979.2
• Gene: TMX4 / 56255
• HGNCID: 25237
• Length: 349
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 126/351 - (35%)
• Similarity: 188/351 - (53%)
• Gaps: 45/351 - (12%)

  Fly     9 AATCAALLLLAATAQSTAAA----QSGLQPGGKLIELDEDNWHLMLQGEWMIEFFAPWCPACKNL 69
            |...|.:..:||||....||    ||.:||      :...||.|:::||||::|:|||||:|:..
Human    12 ALLAAWIAAVAATAGPEEAALPPEQSRVQP------MTASNWTLVMEGEWMLKFYAPWCPSCQQT 70

  Fly    70 APTWERFARVAKDVQVQVAKIDVTTSPSLSGRFFVTALPTIYHVKDGEFRQYRGARDGDALLYFV 134
            ...||.||:..:.:|:.|.|:||...|.||||||||.||..:|.|||.||:|||....:.|..::
Human    71 DSEWEAFAKNGEILQISVGKVDVIQEPGLSGRFFVTTLPAFFHAKDGIFRRYRGPGIFEDLQNYI 135

  Fly   135 KKQQWQSIEPLSAWKKPDTTHMSVLSYFFKLSHTLKHTQKLFKDFNGRLQEEYGLPTWGSYALFA 199
            .:::|||:|||:.||.|.:..||.::..|.:|..:.|....|       ....|:|.|.||..|.
Human   136 LEKKWQSVEPLTGWKSPASLTMSGMAGLFSISGKIWHLHNYF-------TVTLGIPAWCSYVFFV 193

  Fly   200 IATIFVGAALGLLLVCLVDFVYPP------KKSQRQSFSESQDNLTEGLEDLATEEIEDDGDAEE 258
            |||:..|..:||:||.:.:..|.|      ::|::...|| :.:..|.|:|  .||.:||.:.||
Human   194 IATLVFGLFMGLVLVVISECFYVPLPRHLSERSEQNRRSE-EAHRAEQLQD--AEEEKDDSNEEE 255

  Fly   259 NDDEQRDSDEEEQEDDDEEEEDSEEQVGDLATKEKEADSEPEKE----------EKPEPKQAGDA 313
            |.|...|.:||:::..||:|.:.||:..:||....|..||...:          |:.||::|.:.
Human   256 NKDSLVDDEEEKEDLGDEDEAEEEEEEDNLAAGVDEERSEANDQGPPGEDGVTREEVEPEEAEEG 320

  Fly   314 -----APEKTEQV----RKRKPRKGD 330
                 .|..||.|    |:||.:..|
Human   321 ISEQPCPADTEVVEDSLRQRKSQHAD 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5554	NP_001286784.1	PDI_a_TMX	36..136	CDD:239292	44/99 (44%)
TMX4	NP_066979.2	PDI_a_TMX	37..137	CDD:239292	47/105 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..349		39/125 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	99	1.000	Domainoid score	I7107
eggNOG	1	0.900	-	-		E2759_KOG0913
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1481386at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm41981
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3134
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.910