Protein Alignment GlyT and slc6a3

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_571830.1
• Gene: slc6a3 / 80787
• ZFINID: ZDB-GENE-010316-1
• Length: 629
• Species: Danio rerio
• Alignment Length: 638
• Identity: 261/638 - (40%)
• Similarity: 373/638 - (58%)
• Gaps: 69/638 - (10%)

  Fly     4 SSKSGSAGVGG--------VGGGGGVVCPSTAISGCASGTALIQLDATGPGAGG-------AGES 53
            ||.|||:...|        |....||...|:::              ..|||..       ...|
Zfish    22 SSVSGSSSAAGPREVELVLVKEQNGVQFTSSSL--------------RNPGAHSHTHTHTHTHPS 72

  Fly    54 EHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFG 118
            ..:|.||..:.|||||::|::|.|.||||||||||.|||||||:|:.:.:||||:||.:|||:.|
Zfish    73 GQQRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALG 137

  Fly   119 QYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWS 183
            ||...|...|: :.||:|:|:|..:||:|..|..|||:||||.:||:|:||:..|||.:|...|:
Zfish   138 QYNREGAAGVW-KICPIFKGVGFTVILISLYVGSYYNVIIAWALFYLFSSFSGELPWIHCNNTWN 201

  Fly   184 TKYCFSYAQADQCEAT--NGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGL--S 244
            :..|      ....||  |.||                        |..||.|||...||.:  |
Zfish   202 SPNC------SDPNATLLNDTY------------------------KTTPALEYFERGVLHVHES 236

  Fly   245 KGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGAST 309
            .||::.|:.:..|.|||.:...:::..|.|||::|||||:.||..|||||.:|.:||||||||..
Zfish   237 SGIDDLGAPRWQLTACLAVVIVVLYFSLWKGVKTSGKVVWITATMPYVVLTVLLLRGVTLPGAID 301

  Fly   310 GILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATS 374
            ||..||:.|:.:|.:||||.:||.||.|:|...:|.||..|||||||||||:|::|.:..|..||
Zfish   302 GIKAYLSVDFLRLYDAQVWIEAATQICFSLGVGFGVLIAFSSYNKFSNNCYRDAIITSSINSLTS 366

  Fly   375 FFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDS 439
            ||:|.||||.:|:::.:.||.::||...|.||.||:|||.:..||.|.||||:||:||||||:||
Zfish   367 FFSGFVIFSFLGYMSQKHNVALDKVATDGPGLVFIIYPEAIATLPGSSVWAVIFFIMLLTLGIDS 431

  Fly   440 QFALMETVTTAILDRFPNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLI 504
            ....||:|.|.::|.|..|.:::....|.:.:..::..|...||.|:|...|:|.:||..|:|..
Zfish   432 AMGGMESVITGLIDEFKFLHKHRELFTLFIVVSTFLISLICVTNGGIYVFTLLDHFAAGTSILFG 496

  Fly   505 AISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYG 569
            .:.|.|.|||.||..||.:||:.|||:|.   ..:|.:.|::::|..|||::..::..:.|.|||
Zfish   497 VLIEAIGIAWFYGVDRFSDDIEEMIGQRP---GLYWRLCWKFVSPCFLLFMVVVSFATFNPPKYG 558

  Fly   570 HYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAE 622
            .|.:|.||..|||.:.:..::::.|.||.:....|.  ||.|::.:.:.|..:
Zfish   559 SYYFPTWATMVGWCLSISSMIMVPLYAFYKFCSLPG--SFCDKLAYAITPETD 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	242/549 (44%)
slc6a3	NP_571830.1	SLC6sbd_DAT1	76..623	CDD:212083	247/570 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820