DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GlyT and zgc:158427

DIOPT Version :9

Sequence 1:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	XP_017207457.1	Gene:	zgc:158427 / 790932	ZFINID:	ZDB-GENE-061215-110	Length:	579	Species:	Danio rerio

Alignment Length:	576	Identity:	235/576 - (40%)
Similarity:	344/576 - (59%)	Gaps:	37/576 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELS 116
            |...|||.|..:.:|||::.|..||||||||||||||.||||.||||:.:.:|..|:||..:|.:
Zfish     6 EKIEERGFWGKKTEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGVPLFLLETA 70

  Fly   117 FGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPA 181
            .||:...|.:..:.|.|||.:|:|....|......:|:.:|:||.:||:.:||:..|||.:|:..
Zfish    71 MGQFTHEGGITCWHRLCPLAQGIGYAGQLTVLYSCMYFTIILAWALFYLISSFSSQLPWASCDNI 135

  Fly   182 WSTKYCFSYAQADQCEATNGTYYLRTCH---NATSAAENNITTLALGALKRPPAEEYFNNFVLGL 243
            |:|..|.:.|      |.|.|:. ||..   |:|||                 |.|::...||.|
Zfish   136 WNTDNCVNLA------AGNLTFN-RTTQMLINSTSA-----------------ATEFWERRVLSL 176

  Fly   244 SKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGAS 308
            |.|||:.|.|...:..||...|.|.:.|:.|||:|:||||||||.||||:|::|.:||:|||||.
Zfish   177 SGGIEDIGKINWEILLCLIAMWIICYFCIWKGVKSTGKVVYFTATFPYVMLIVLLIRGLTLPGAL 241

  Fly   309 TGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIAT 373
            .||:|||.|:..:||:.|||.:|..||||:.|...|.||:|.|||:::||||:|...:...|..|
Zfish   242 QGIVFYLYPEPARLADPQVWMEAGTQIFFSYSVIGGVLISLGSYNQYNNNCYRDCFWLCLLNSGT 306

  Fly   374 SFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLD 438
            ||.||..:||::||:||...|.:|:|.:.|.|||||.||:.|..:|...:|||.||:|::.||||
Zfish   307 SFVAGFAVFSVLGFMAHVQGVPIEEVAESGPGLAFIAYPQAVAMMPFPQLWAVCFFIMIILLGLD 371

  Fly   439 SQFALMETVTTAILDRFPN-LRQ--YKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWS 500
            :||..:|.|.|:::|.||. ||:  .:..:||.:.:..:.|.|...|..|||..||.|.||.|.:
Zfish   372 TQFVSVECVITSVMDLFPEVLRRAGRRELLVLLLCLTCFFGQLIMVTEGGMYVFQLFDNYACNGA 436

  Fly   501 VLL-IAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYK 564
            .|| :::.|.:.|.||:|:::..:.|:.|...|.   |:::.:.|:|:||...|....::.|.|.
Zfish   437 CLLFLSVFESLAIGWIFGAEKMFDIIEDMTESRP---NYWFMLCWKYLTPLVSLTSFVYSMVRYT 498

  Fly   565 PAKYGH-YVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQP 619
            |..:.. |:||.||..:||::.|..:|::...|..::.....||  :.|.:||..|
Zfish   499 PLTFNRWYIYPDWAYVLGWLLALSSILLVPAWALGQMCAGKGSL--KQRWRHLSSP 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	227/553 (41%)
zgc:158427	XP_017207457.1	SLC6sbd-TauT-like	11..552	CDD:271387	232/569 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820