Protein Alignment GlyT and Slc6a19

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_083154.1
• Gene: Slc6a19 / 74338
• MGIID: 1921588
• Length: 634
• Species: Mus musculus
• Alignment Length: 619
• Identity: 218/619 - (35%)
• Similarity: 317/619 - (51%)
• Gaps: 126/619 - (20%)

  Fly    52 ESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELS 116
            |....|..|..:..::|:.:|:.|||||||||||||.::|||||:|||.|:||..|:||:::|.:
Mouse    27 EEAGSRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLYLEFA 91

  Fly   117 FGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPA 181
            .||....|.:.|:....|..:|:|...:.||.:|.||||.||||.::|.|.||...|||..|
Mouse    92 IGQRLRKGSMGVWSSIHPALKGIGIASMFVSFMVGLYYNTIIAWVMWYFFNSFQEPLPWSEC--- 153

  Fly   182 WSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYF-NNFVLGLSK 245
                      ..:|    |.|.|:..|..::|.                   :|| ....|.:|.
Mouse   154 ----------PLNQ----NQTGYVEECAKSSSV-------------------DYFWYRETLNIST 185

  Fly   246 GIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTG 310
            .|.::|||:..:..||..||:::::|:.:|::::||.||.|:..|||||.|..:||:||.||:.|
Mouse   186 SISDSGSIQWWILLCLTCAWSVLYVCIIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNG 250

  Fly   311 ILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSF 375
            |:|..||:..:|:|...|.||..|:|::.|.|:||||:.||||...|||..||:||:..|..||.
Mouse   251 IVFLFTPNITELSNPNTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEMDSVIVSVINGFTSV 315

  Fly   376 FAGLVIFSIIGFLAHE-----LNVDVEKVVD---------------------------------- 401
            :|..|::|||||.|.|     :|.::..:::
Mouse   316 YAATVVYSIIGFRATERFDDCVNTNILTLINGFDLPEGNVTSENFEAYQQWCNATNPQAYAQLKF 380

  Fly   402 -------------QGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILD 453
                         :|.||||||:.|.:|::||||:|:||||:||..|||.|.|..||.|...:.|
Mouse   381 QTCDINSFLSEGVEGTGLAFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQD 445

  Fly   454 RFPNLRQYKIW--------VVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECI 510
            .  |:...| |        :.|...:..:|    ||.|||.|||.|:|.:|.:..:|:||..|..
Mouse   446 L--NITPKK-WPKELLTGLICLGTYLIAFI----FTLNSGQYWLSLLDSFAGSIPLLIIAFCEMF 503

  Fly   511 LIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLL--FILFF--------------- 558
            .:.::||..||..||:.|||.:.   |.||.:.||.::|..:|  |:.||
Mouse   504 AVVYVYGVDRFNKDIEFMIGHKP---NIFWQVTWRVVSPLIMLVIFLFFFVIEVNKTLMYSIWDP 565

  Fly   559 NWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVI 592
            |:.|:  .|.....||.|..||...|..:|.|.|
Mouse   566 NYEEF--PKSQKIPYPNWVYAVVVTVAGVPCLSI 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	217/614 (35%)
		Herpes_BLLF1	<884..1135	CDD:282904
Slc6a19	NP_083154.1	SLC5-6-like_sbd	32..612	CDD:444915	217/614 (35%)