Protein Alignment GlyT and slc6a1a

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001038752.2
• Gene: slc6a1a / 692318
• ZFINID: ZDB-GENE-060519-23
• Length: 679
• Species: Danio rerio
• Alignment Length: 691
• Identity: 269/691 - (38%)
• Similarity: 389/691 - (56%)
• Gaps: 89/691 - (12%)

  Fly    56 ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQY 120
            :|.||.|:||||||.:||::||||||||||||..|||||||||:.:.|:.||:||.|:|.:.|||
Zfish    42 DRETWGGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLECALGQY 106

  Fly   121 AALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTK 185
            .::|.:.|: :..|:|:|:|....::|..:.:||.:||||.::|::.||...|||::|...|:|.
Zfish   107 TSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIIAWALYYLYNSFTTDLPWKSCNNPWNTD 170

  Fly   186 YCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKGIEET 250
            .|:          ||  |.:....|.|||                 ..|::...|..::.|:|:.
Zfish   171 RCY----------TN--YSIVDTTNLTSA-----------------VMEFWERNVHQMTDGLEKP 206

  Fly   251 GSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYL 315
            |.|::.||..|.:||.:|:.|:.|||..:||||||:|.:||.:|.|||:||||||||..|||||:
Zfish   207 GEIRVPLAITLAIAWVLVYFCIWKGVSWTGKVVYFSATYPYFMLFILFIRGVTLPGAKEGILFYI 271

  Fly   316 TPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLV 380
            |||:::|..::||.|||.||||:.....|.||.|.|||.|:||.|:||:||...|..||.|||.|
Zfish   272 TPDFEKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYRDSIIVCCINSFTSMFAGFV 336

  Fly   381 IFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALME 445
            ||||:||::|.....:..|...|.||||:.|||.||:|||||:||:|||.|||.||:||||..:|
Zfish   337 IFSIVGFMSHVTKRPIADVAASGPGLAFLAYPEAVTQLPVSPLWAILFFSMLLMLGIDSQFCTVE 401

  Fly   446 TVTTAILDRFPN-LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLL-IAISE 508
            ...||::|.||. ||:.:...:..|.:..|..||...|..|:|..:|.|.|:|:...|| :...|
Zfish   402 GFITALVDEFPRLLRKRREIFIACVCVVSYAIGLSNITQGGLYVFKLFDYYSASGMCLLFLVFFE 466

  Fly   509 CILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVY 573
            ||.|:|.||..:|.::||.|||.:...|   |.:.|.:.||..:..:..|:.|:..|....:||:
Zfish   467 CISISWCYGVNKFYDNIQEMIGYKPCIW---WKLCWVFFTPLVVAGVFLFSAVQMVPLTMNNYVF 528

  Fly   574 PMWADAVGWIVGLLPVLVI-------FLVAFQEIWRAPMSLSFRDRIKHLLQPTA-----EWGPA 626
            |.|...|||::.|..:::|       ||         .:..::::||:.:|||.|     |.||
Zfish   529 PKWGQGVGWLMALSSMVLIPGYMGYMFL---------NLKGTYKERIRIMLQPPAVKRAQENGP- 583

  Fly   627 GRPCVNLHAERYQSQNYDGVTNTKILIEEEASPKQAANKKDRQLTLDVDVDVECLPLATVGKRPG 691
                     |:.|||       ..|   :|.||:|..:.:..|..|.             .:.|.
Zfish   584 ---------EQQQSQ-------PPI---QEQSPQQPQSPQQPQSPLQ-------------PQSPQ 616

  Fly   692 APKSMGKQGSSGNLQTNAKNGTHKSPTTEISPSKQPLIPSE 732
            .|:|..:..|....|:..:..:.:.|.......:||..|.:
Zfish   617 QPQSPEQPQSPQQPQSPQQPQSPQQPQPPDQAPQQPQSPPQ 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	240/554 (43%)
slc6a1a	NP_001038752.2	SLC5-6-like_sbd	2..588	CDD:294310	250/597 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000575
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920