Protein Alignment GlyT and slc6a4b

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001170930.1
• Gene: slc6a4b / 664770
• ZFINID: ZDB-GENE-060314-2
• Length: 591
• Species: Danio rerio
• Alignment Length: 598
• Identity: 234/598 - (39%)
• Similarity: 359/598 - (60%)
• Gaps: 55/598 - (9%)

  Fly    40 LDATGPGAGGAGESEH---------ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAF 95
            |.|.|| ...||.:.:         .|..|:.:.|||||::|::|.|||||||||:||.||||||
Zfish    13 LCAPGP-PNNAGYNSNPVPVIIQTESRDKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAF 76

  Fly    96 LIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAW 160
            |||:.:|.|..|:||.:|||:.||:...|.:::::..||:|:|:|..:.:::..|..|||.||||
Zfish    77 LIPYVLMAVFGGVPLFYMELALGQFHRTGAISIWKHICPIFKGIGFAICIIALYVSFYYNTIIAW 141

  Fly   161 TIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALG 225
            .:||.::||:..|||.:|:..|:|:.|.:|...|....||
Zfish   142 ALFYFYSSFSSTLPWTSCDNDWNTENCTNYFGKDNVTWTN------------------------- 181

  Fly   226 ALKRPPAEEYFNNFVLGL--SKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTAL 288
             ..|.||||::...||.:  |.|:...|.|:..|..||||.:|||:..|.|||::|||||:.||.
Zfish   182 -YSRSPAEEFYTRNVLAVHESSGLGNVGYIRWQLMLCLFLIFTIVYFSLWKGVKTSGKVVWVTAT 245

  Fly   289 FPYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYN 353
            .|||||:||.:||.|||||..|::|||.|.|::|....||.|||.||||:|.|.:|.|:.|||||
Zfish   246 LPYVVLLILMIRGATLPGAWKGVVFYLNPKWEKLKETSVWVDAAAQIFFSLGPGFGVLLALSSYN 310

  Fly   354 KFSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVV-DQGAGLAFIVYPEVVTR 417
            .|:||||:|:::.:..|..|||.:|.|||:::|::|.:.||:||.|. |:|..|.||.|||.:..
Zfish   311 PFTNNCYRDAIVTSLVNCLTSFVSGFVIFTVLGYMAEQRNVNVEDVARDKGPSLLFITYPEAIAN 375

  Fly   418 LPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPNLRQYKIWV-VLSVAIFGYIGGLGFT 481
            :..|..:|::||||::||||||.|..:|.:.||::|.:|::..::..: ||.:.:..::|.|...
Zfish   376 MVGSTFFAIIFFVMMITLGLDSTFGGLEAIITAVMDEYPDVLSHRRELFVLGLVVVCFLGSLSTL 440

  Fly   482 TNSGMYWLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRY 546
            |..|.|.::|::::....|::.|...|...::|.||..||.|||:.|:|   :....||.:.|..
Zfish   441 TKGGAYVVKLLEEFGVGSSIIAIVFLEATAVSWFYGINRFSNDIKSMLG---YTPGLFWKVCWVA 502

  Fly   547 ITPATLLFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGL-----LPVLVIFLVAFQEIWRAPMS 606
            |:||.|.:|:..:.:..:......|.:|.|:..||:|:|.     :|:.:::.:    :| .|.|
Zfish   503 ISPAFLAYIIISSLLNPQTLTLFDYEFPDWSITVGYIIGASSFIWIPIYMVYKL----VW-TPGS 562

  Fly   607 LSFRDRIKHLLQP 619
            |  :.|:...|:|
Zfish   563 L--KQRLAVCLRP 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	222/554 (40%)
slc6a4b	NP_001170930.1	SLC6sbd_SERT	38..574	CDD:271399	228/572 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820