Protein Alignment GlyT and slc6a4a

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001035061.1
• Gene: slc6a4a / 664719
• ZFINID: ZDB-GENE-060314-1
• Length: 646
• Species: Danio rerio
• Alignment Length: 647
• Identity: 249/647 - (38%)
• Similarity: 372/647 - (57%)
• Gaps: 71/647 - (10%)

  Fly     3 QSSKSGSAGVGGVGGGGGVVCPSTAISGCASG-----------TALIQLDATGPGAGGAGESEHE 56
            :..|||| |.|.|..|.....|.:...|..:|           |.::|..:..|          .
Zfish    37 KDQKSGS-GPGQVSNGYRSTSPQSPKEGAGTGTDRVNTPGTFRTLVVQQTSLDP----------P 90

  Fly    57 RGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYA 121
            |.||:.:.|||||::||:|.|||||||||:||.|||||||:|:.:|.|..|:||.:|||:.||:.
Zfish    91 RETWSKKMDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYLLMAVFGGVPLFYMELALGQFH 155

  Fly   122 ALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKY 186
            ..|.:::::..||:|:|:|..:.:::..:..|||.|:||.::|:.:||...|||..|...|:|..
Zfish   156 RSGCISIWKHVCPIFKGIGFAICIIALYIAFYYNTIMAWALYYLLSSFRATLPWTTCNNRWNTPN 220

  Fly   187 CFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVL--GLSKGIEE 249
            |              |:||.|..| .|...|:|:          ||||::...||  .||.|:.:
Zfish   221 C--------------THYLSTDLN-VSWTNNSIS----------PAEEFYVRQVLQVHLSPGLHQ 260

  Fly   250 TGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFY 314
            .|.:...||.||...:|:|:..:.|||::|||||:.||.|||:||:||.:||.|||||..|::||
Zfish   261 LGWVSWQLALCLLFIFTVVYFSIWKGVKTSGKVVWVTATFPYLVLLILLIRGATLPGAWRGVVFY 325

  Fly   315 LTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGL 379
            |.||||:|....||.|||.||||:|.|.:|.|:..:|||.|.||||||:||.:..|..|||.:|.
Zfish   326 LKPDWKKLLTTTVWLDAAAQIFFSLGPGFGVLLAFASYNPFHNNCYKDALITSSVNCLTSFLSGF 390

  Fly   380 VIFSIIGFLAHELNVDVEKVV-DQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFAL 443
            |||:::|::|......||.|. |.|..|.||:|.|.:..:|.:..:|::||:|::.|||||.||.
Zfish   391 VIFTVLGYMAEMRQQGVETVAKDAGPSLLFIIYAEAIANMPAATFFAIIFFLMIIMLGLDSTFAG 455

  Fly   444 METVTTAILDRFPN-LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAIS 507
            :|.|.||:||.||: |.:.:.|.||.:....|:|.|...|..|.:.::|.::||...:|:.:...
Zfish   456 LEGVITAMLDEFPHLLARRREWFVLGLVCVCYLGALSTLTYGGAFVVKLFEEYATGPAVITVVFL 520

  Fly   508 ECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKP-AKYGHY 571
            |.|.::|.||:.||.||:|.|:|   :....||.:.|..|.|..||||: .:::.:.| .|...|
Zfish   521 EVIAVSWFYGTTRFCNDVQLMLG---FAPGLFWRVCWIAICPCFLLFII-VSFLAFPPEVKLFDY 581

  Fly   572 VYPMWADAVGWIVGL-----LPVLVIF-LVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAG 627
            :||.|...:|:.:|:     :|..::: ||..:.        :|:.|:...:.|.|. |.:|
Zfish   582 LYPFWTTVLGYCIGVSSFICVPSYMVYHLVTTKG--------TFQQRLLKGITPEAP-GSSG 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	229/550 (42%)
		Herpes_BLLF1	<884..1135	CDD:282904
slc6a4a	NP_001035061.1	SLC5-6-like_sbd	91..628	CDD:444915	231/573 (40%)