DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlyT and si:ch211-132b12.6

DIOPT Version :9

Sequence 1:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_001038523.1	Gene:	si:ch211-132b12.6 / 564583	ZFINID:	ZDB-GENE-050420-179	Length:	577	Species:	Danio rerio

Alignment Length:	574	Identity:	238/574 - (41%)
Similarity:	346/574 - (60%)	Gaps:	35/574 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELS 116
            |...|||.|..:.:|||::.|..||||||||||||||.||||.||||:.:.:|..||||..:|.:
Zfish     6 EEIEERGFWGKKAEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGLPLFLLETA 70

  Fly   117 FGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPA 181
            .||:...|.:..:.|.|||.:|:|....|......:||.:|:||.:||:.:||:..|||.:|...
Zfish    71 MGQFTHEGGITCWHRLCPLAQGVGYAGQLTVLYSCMYYTIILAWALFYLVSSFSSQLPWVSCNNI 135

  Fly   182 WSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKG 246
            |:|..|.:.|      |.|.|:...|..|:|||                 |.|::...||.||.|
Zfish   136 WNTDNCVNLA------AGNLTFNRTTLANSTSA-----------------ATEFWERRVLSLSGG 177

  Fly   247 IEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGI 311
            ||:.|.|...:..||...|.|.:.|:.|||:|:||||||||.||||:|::|.:||:|||||..|:
Zfish   178 IEDIGKINWEILLCLIAMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGV 242

  Fly   312 LFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFF 376
            :|||.|:..:||:.|||.:|..|:||:.|...|.||:|.|||::|||||:||..:...|..|||.
Zfish   243 VFYLYPEPARLADPQVWMEAGTQVFFSYSVCSGILISLGSYNQYSNNCYRDSFWLCLLNSGTSFV 307

  Fly   377 AGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQF 441
            ||..:||::||:||...|.||:|.:.|.|||||.||:.:..:|...:|||.||:|::.|||||||
Zfish   308 AGFAVFSVLGFMAHVQGVPVEEVAESGPGLAFIAYPQAMAMMPFPQLWAVCFFIMIILLGLDSQF 372

  Fly   442 ALMETVTTAILDRFPN-LR---QYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVL 502
            ..:|.|.|:::|.||. ||   :.:::|:| :.:..:.|.|...|..|||..||.|.||.|.:.|
Zfish   373 VGIECVITSVMDLFPEVLRRAGRRELFVLL-LCLTCFFGQLIMVTEGGMYVFQLFDNYACNGACL 436

  Fly   503 L-IAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPA 566
            | :::.|.:.|.|::|:::..:.|:.|...|.   |:::.:.|:|:||...|....::.|.|.|.
Zfish   437 LFLSVFESLAIGWLFGAEKMFDIIEDMTESRP---NYWFMLCWKYLTPLVSLMSFVYSMVRYTPL 498

  Fly   567 KYGH-YVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQP 619
            .:.. ||||.||.|:||::.|..:|::...|..::|....:|  :.|..||..|
Zfish   499 TFNRWYVYPDWAYALGWLLALSSILLVPGWALGQMWAGKGTL--KQRWGHLCSP 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	231/551 (42%)
si:ch211-132b12.6	NP_001038523.1	SLC6sbd-TauT-like	11..550	CDD:271387	235/567 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920