Protein Alignment GlyT and slc6a7

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_005161359.1
• Gene: slc6a7 / 562050
• ZFINID: ZDB-GENE-070112-1492
• Length: 652
• Species: Danio rerio
• Alignment Length: 664
• Identity: 271/664 - (40%)
• Similarity: 386/664 - (58%)
• Gaps: 75/664 - (11%)

  Fly    17 GGGGVVCPSTAISGCASG--TALIQLDATGPGAGGAGESEHERGTWTGRFDFLLSLLGYSVGLGN 79
            |.|.:..|||......:|  ::.:...:..|.:..:..::..|..|.|:::||||.:||.|||||
Zfish    29 GNGVITTPSTENPAHQNGAVSSPVASQSQPPSSAASPPAQPPRDQWGGKYEFLLSCIGYCVGLGN 93

  Fly    80 VWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMI 144
            |||||||||.||||.||||:.|||...|:||..||||.|||.|.||:.|: :.|||.:|:|.||:
Zfish    94 VWRFPYLCYRNGGGVFLIPYFIMLFFTGMPLFLMELSLGQYGAAGPITVW-KCCPLLKGIGIGML 157

  Fly   145 LVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCH 209
            .||.:|.||||:|||||.:|:.:||...|||                   .|:|...   :..|.
Zfish   158 CVSTLVCLYYNVIIAWTFYYLGSSFQSPLPW-------------------SCDALQN---IALCA 200

  Fly   210 NATSAAENNITTLALGALKRPPAEEYFNNFVLGL--SKGIEETGSIKLSLAACLFLAWTIVFLCL 272
            |.|::.::             |:|.::|..|||:  |.|:.:.|.::..||.||..||.|:|||:
Zfish   201 NKTNSTQS-------------PSEVFWNEKVLGVVHSTGLSDPGPVRWPLALCLLAAWIIIFLCM 252

  Fly   273 CKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFF 337
            .||:.|||||||.||.|||.||::|.:||.||.|:..|:.|||||.|.|||:||||.|||.|||:
Zfish   253 LKGIHSSGKVVYVTATFPYFVLLVLIIRGATLEGSLDGVAFYLTPKWDQLADAQVWNDAASQIFY 317

  Fly   338 ALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQ 402
            :|....|||::::|||||.||..:|::|:...|.:||||||..||||:|.:|.:..|.|:||.|.
Zfish   318 SLGIGVGGLLSMASYNKFDNNVIRDTIIITIGNCSTSFFAGFAIFSILGHMAFKKGVPVDKVADS 382

  Fly   403 GAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPNLR---QYKIW 464
            |.||||:.|||.:..||.|..|::|||:||..||:|:.|..||.:.||:||.||.||   ::|.
Zfish   383 GPGLAFVAYPEALALLPGSVFWSILFFLMLFMLGVDTLFGNMEGICTAVLDEFPQLRSNLKHKT- 446

  Fly   465 VVLSVAIFG-YIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGM 528
            :.|:|..|. |:.||...|:.|:||..|:|.::.::.:::|.:..||.|::.||..:|..||..|
Zfish   447 LFLAVLCFSFYLMGLLLITDGGIYWFTLIDSFSTSFGLIIITLFMCIGISFFYGVNQFCQDIVDM 511

  Fly   529 IGK-RSWFWN--FFWGIMWRYITPATLLFILFFNWVE-YKPA-KYGHYVYPMWADAVGWIVGLLP 588
            |.: ..|...  .::...|...||..|.|||.:.::| |:.: :||.||||:|..|:|..:|.|.
Zfish   512 ICRCPPWCTKMLLYFKACWVVFTPFLLTFILTYIFIEMYRTSLRYGSYVYPIWGKALGVCMGALC 576

  Fly   589 VLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEW--------------------GPAGRPCVNL 633
            .|.|.:.|...|  :..|.:.:||.|..::|...|                    ||.   .|||
Zfish   577 CLQILIWAIVAI--SKESGTLKDRFKKSIRPLNSWRVNNINSSSQEQHVEPHTIEGPF---TVNL 636

  Fly   634 HAERYQSQNYDGVT 647
            ....|...|::|::
Zfish   637 TEADYTGMNWEGIS 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	250/556 (45%)
slc6a7	XP_005161359.1	SLC5-6-like_sbd	71..610	CDD:294310	255/577 (44%)
		PotE	<235..564	CDD:223605	154/329 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100873
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720