Protein Alignment GlyT and Slc6a12

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_059031.1
• Gene: Slc6a12 / 50676
• RGDID: 620255
• Length: 628
• Species: Rattus norvegicus
• Alignment Length: 589
• Identity: 251/589 - (42%)
• Similarity: 360/589 - (61%)
• Gaps: 55/589 - (9%)

  Fly    56 ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQY 120
            :||.||.:.:|:||:.|..:|||||||||||||.||||||.||:.|.....|:|:.|:|::.|||
  Rat    49 DRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQY 113

  Fly   121 AALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTK 185
            ::.|.|..:|:.|||.:|:|...:::.:.:.:||.:|:||.:||:|:||...|||..|..:|:|:
  Rat   114 SSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTE 178

  Fly   186 YCFSYAQADQCEATNGTYYLRTCHNATSAA--ENNITTLALGALKRPPAEEYFNNFVLGLSKGIE 248
            :|..:..                :::|.||  ..|.|:         |..|::...|||::.||.
  Rat   179 HCVDFLN----------------YSSTRAASYSENFTS---------PVMEFWERRVLGITSGIH 218

  Fly   249 ETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILF 313
            :.||::..||.||.|||.|.:.|:.|||:|:||||||||.|||::|:||.:||||||||..||:|
  Rat   219 DLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVF 283

  Fly   314 YLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAG 378
            ||.||..:|.:.|||.||..||||:.:...|.|..|.||||:.||||:||:.:.|.|.||||.||
  Rat   284 YLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAG 348

  Fly   379 LVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFAL 443
            .|:|||:||:|.|..|.:.:|.:.|.|||||.:|:.||.:|:|.:|:.|||:|||.|||||||..
  Rat   349 FVVFSILGFMAQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFLMLLFLGLDSQFVC 413

  Fly   444 METVTTAILDRFP---NLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLL-I 504
            ||.:.||.:|.||   ..|..:..::|:|||..|:.||...|..|||..||.|.||::...|| :
  Rat   414 MECLVTASMDMFPQQLRKRGRRELLILAVAIVCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFL 478

  Fly   505 AISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYG 569
            ::.|.|.|.|:||:.||.::::.|||.|.|   ....|.|.::||...|...||:..:|.|.||.
  Rat   479 SLFEVICIGWVYGADRFYDNVEDMIGYRPW---PLVKISWLFLTPGLCLATFFFSLSKYTPLKYN 540

  Fly   570 H-YVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSL---------SFRDRIKHLLQPTAEWG 624
            : |:||.|..::||           |:||..:...|:.:         ||:.|::.|:.|.....
  Rat   541 NVYIYPSWGYSIGW-----------LLAFSSMACVPLFIIITLLKTQGSFKKRLQRLITPDPSLP 594

  Fly   625 PAGR 628
            ..||
  Rat   595 QPGR 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	241/546 (44%)
		Herpes_BLLF1	<884..1135	CDD:282904
Slc6a12	NP_059031.1	SLC5-6-like_sbd	49..589	CDD:444915	248/578 (43%)