Protein Alignment GlyT and slc6a9

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_005163551.1
• Gene: slc6a9 / 494490
• ZFINID: ZDB-GENE-050105-3
• Length: 653
• Species: Danio rerio
• Alignment Length: 674
• Identity: 286/674 - (42%)
• Similarity: 425/674 - (63%)
• Gaps: 43/674 - (6%)

  Fly    35 TALIQLDATG--PGAGGAGESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLI 97
            ||.:..|..|  ||.....:....||.|..:.:|:|:.:||:||||||||||||||.||||||:.
Zfish     7 TAAVMADQNGAVPGEPVKRDENSRRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMF 71

  Fly    98 PFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTI 162
            |:.||||..|:||.|:||||||:.:||.:.|: :..|:|:|:|.||::||..:.:|||::|....
Zfish    72 PYFIMLVFCGIPLFFLELSFGQFTSLGCLGVW-KVSPMFKGVGYGMMVVSTYIGIYYNVVICIAF 135

  Fly   163 FYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGAL 227
            :|.|.|...:|||..|...|:|..|.......:..||...         .||..:.:|.:.....
Zfish   136 YYFFMSMTNLLPWTYCNNPWNTPDCSGVVSTHRANATFAN---------MSAVVSGVTEIVNRTK 191

  Fly   228 KRPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYV 292
            :..|:|||:.|:||.:|.||...|.::|.:..||.::|.:|||||.:||:||||||||||.||||
Zfish   192 RTSPSEEYWRNYVLNISDGIGNFGEVRLPILGCLAVSWFVVFLCLIRGVKSSGKVVYFTATFPYV 256

  Fly   293 VLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSN 357
            ||.|||:||:||.||.:||.:||||.|:::.:|:||||||.|||::|..|||||||::|||||.|
Zfish   257 VLTILFIRGITLDGAISGIKYYLTPQWQKILDAKVWGDAASQIFYSLGCAWGGLITMASYNKFHN 321

  Fly   358 NCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSP 422
            ||::||:|::..|..||.:||.|||||:||:||.|.|||.:|.|.|.||||:.|||.:|.||:||
Zfish   322 NCFRDSIIISVTNCGTSVYAGFVIFSILGFMAHHLGVDVSEVADHGPGLAFVAYPEALTLLPISP 386

  Fly   423 VWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPN--LRQYKIWVVLSVAIFGYIGGLGFTTNSG 485
            :|::|||.||:.|||.:||.|:||:.||::|....  :.:.|.:|.|.|||.|::.|:..||.:|
Zfish   387 LWSLLFFFMLILLGLGTQFCLLETLVTAVVDEIGTDWIIKNKTYVTLGVAIIGFLLGVPLTTQAG 451

  Fly   486 MYWLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNF----FWGIMWRY 546
            :|||.|||.|||::|:::|:...||.|.::||.:.:..|::.|:|       |    |:.|.|||
Zfish   452 IYWLLLMDNYAASFSLVIISCIMCICIMYVYGHKNYFKDVEMMLG-------FPPPIFFRICWRY 509

  Fly   547 ITPATLLFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGL-----LPVLVIFLVAFQEIWRAPMS 606
            ::|..:.|||.|..::|||..|..||||.|:..:|:.:.|     :|:..:|.:|..|      .
Zfish   510 VSPFIITFILIFTVIQYKPITYNDYVYPGWSLVIGFAMALSSVICIPIYALFKIAMSE------G 568

  Fly   607 LSFRDRIKHLLQPTAEWGPAGRPCVNLHAE-RYQSQNYDG--VTNTKILIEEEASPKQAANKKDR 668
            .:|.:|:|:.::|..:||||    :..|.: ||.:...:.  |:..|..:::|...|....:|:.
Zfish   569 STFLERLKNSVKPDPDWGPA----LQEHRKGRYATAGPESVEVSPLKEDLKDEGKDKLTEKEKET 629

  Fly   669 QLTLDVDVDVECLPLATVGKRPGA 692
            :...::.:.:.....:|:...|.|
Zfish   630 EKKDEIGLTIPGSNGSTLNPTPSA 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	261/556 (47%)
slc6a9	XP_005163551.1	SLC6sbd_GlyT1	15..598	CDD:212067	274/609 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	568	1.000	Domainoid score	I220
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	584	1.000	Inparanoid score	I969
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26298
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11616
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10344
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	8.000