Protein Alignment GlyT and slc6a5

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001009557.1
• Gene: slc6a5 / 494450
• ZFINID: ZDB-GENE-050105-2
• Length: 786
• Species: Danio rerio
• Alignment Length: 650
• Identity: 304/650 - (46%)
• Similarity: 416/650 - (64%)
• Gaps: 56/650 - (8%)

  Fly    25 STAISGCASGTALIQLDATGPGA------------GGAGESEHERGTWTGRFDFLLSLLGYSVGL 77
            :|.|.|....|:::....|||..            ...|:....||.|:.:.||:||::||:|||
Zfish   133 TTIILGTDGNTSVLPGTVTGPPTDDTGRLFQDDDDDDGGDENKARGNWSNKLDFILSMVGYAVGL 197

  Fly    78 GNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTG 142
            |||||||||.:.|||||||||:.|||.:||:|:..:|:|.||:|:.|||:|::.. |..:|.|..
Zfish   198 GNVWRFPYLAFQNGGGAFLIPYLIMLGLAGIPIFLLEVSLGQFASQGPVSVWKAI-PALQGCGIA 261

  Fly   143 MILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRT 207
            |:::|.::.:|||:|:.||::|:|||....|||..|:..|:|..|          .......|.|
Zfish   262 MLIISVLIAIYYNIIMCWTLYYLFASLKETLPWATCKNEWNTVEC----------KDKDMLLLDT 316

  Fly   208 C----HNATSAAENNITTLAL-----GALKR------------PPAEEYFNNFVLGLSKGIEETG 251
            |    .|.||...   ||..|     |.|.:            .|:||||...||.:|||||..|
Zfish   317 CILRDRNITSIKN---TTFCLSANVVGNLSKLLNVTVDNKTYVSPSEEYFKYNVLHISKGIEYPG 378

  Fly   252 SIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLT 316
            .|:..|||||||||.||:..|.||::||||||||||.|||||||||.:||||||||.:|||:::|
Zfish   379 DIRWPLAACLFLAWLIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGSGILYFIT 443

  Fly   317 PDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVI 381
            |.|::|.:|:||.|||.||||:||.||||||||||||||.||||:|:|||...|.|||.|||.||
Zfish   444 PKWEKLNDAKVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVI 508

  Fly   382 FSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMET 446
            ||:|||:||||.|.:|.|.|:|.|:||:||||.:||||:||.||::||:||||||||:.||.:||
Zfish   509 FSVIGFMAHELKVPIESVADEGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIET 573

  Fly   447 VTTAILDRFPN-LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECI 510
            :.|::.|.||. ||::|....|...:..::.|....|.||||.|||:|.:||::|:::|||.|.:
Zfish   574 IVTSVSDEFPKYLRKHKPQFTLVCCLSFFVLGFPMITESGMYMLQLVDTFAASYSLVIIAIFELV 638

  Fly   511 LIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVYPM 575
            .|::|||.|||..||:.|||.:.   |.||.:.|.::||..|.|||..:..::|...|..|.||.
Zfish   639 GISYIYGLQRFCEDIEMMIGFQP---NKFWRVCWAFVTPTILTFILALSLYQWKVMTYEDYTYPN 700

  Fly   576 WADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAGRPCVNLHAERYQS 640
            |:..:||::.:..|:.|.::...::..||.||.  :|:|.:..|..:|||.   .:....|||::
Zfish   701 WSMVLGWLMVICSVIWIPIMFAIKMHLAPGSLI--ERLKLVCSPQPDWGPF---LMKHRGERYKN 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	283/567 (50%)
slc6a5	NP_001009557.1	SLC5-6-like_sbd	177..775	CDD:294310	296/605 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	568	1.000	Domainoid score	I220
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37901
Inparanoid	1	1.050	584	1.000	Inparanoid score	I969
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26298
orthoMCL	1	0.900	-	-		OOG6_100873
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10344
SonicParanoid	1	1.000	-	-		X6052
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.760