DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GlyT and CG1698

DIOPT Version :9

Sequence 1:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster

Alignment Length:	616	Identity:	227/616 - (36%)
Similarity:	341/616 - (55%)	Gaps:	41/616 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 ATGPGAGG------AGESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFT 100
            |..||.|.      ||:...:|.:|....:||:|.:..|||||||||||:....||||||:||:.
  Fly    53 APPPGHGDSPSGVEAGQPGKKRDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYL 117

  Fly   101 IMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYM 165
            |:|::.|.|:.::|:..||:::.|.|.|| .|.|:.||:|.|.:|.:.||..||..::|.|:.|.
  Fly   118 IVLILVGKPVYYLEMLLGQFSSRGSVKVY-DFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYF 181

  Fly   166 FASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRP 230
            ..||.|.|||..|...|.|:                      |.::.....:..|:||...::..
  Fly   182 VDSFYPTLPWSYCREEWGTE----------------------CLDSGPQEASRATSLAGSGVRTT 224

  Fly   231 PAEEYFNNFVLGLSKGIEE-TGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVL 294
            .||.||.|.:|.....|:: .|....|||..|.:||.::...:.|||:||||..||.|||||||:
  Fly   225 SAEFYFTNIILREKASIDDGIGYPSWSLALALAVAWIVIAGIMFKGVKSSGKASYFLALFPYVVM 289

  Fly   295 VILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNC 359
            ::|.||.:|||||..|:|::|.|.|.:|...|||..|..|:||:|:..:|.:|..:|||:|.:|.
  Fly   290 LVLLVRALTLPGAFDGVLYFLRPQWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYASYNRFGHNI 354

  Fly   360 YKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELN-VDVEKVVDQGAGLAFIVYPEVVTRLPVSP- 422
            |:|:.||...:..||..:|::||.|:|.||:|.| .|:..||:.|.|||||.||:.:.:....|
  Fly   355 YRDANIVTTLDTFTSLLSGVIIFGILGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQ 419

  Fly   423 VWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMY 487
            :::||||:||..||:.|...:...::|.|.|:|.:|:.:.  ||:.:||.||..||.:.|..|.:
  Fly   420 LFSVLFFLMLFVLGIGSNVGMASCMSTVIKDQFGHLKNWT--VVVGIAIVGYFLGLLYITPGGQF 482

  Fly   488 WLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATL 552
            .|.|:|.:...:..|::||.|.:.||||||.:|...|::.|||.::   :.::.|.|..:||..:
  Fly   483 LLNLVDYFGVTFVALVLAIFELVTIAWIYGVKRLCRDVEFMIGIKT---SLYYRICWAVVTPLLM 544

  Fly   553 LFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLL 617
            |.||.:..|.|:|.||..|.|.......||.:....|..:...|...:.:.|..|....||:...
  Fly   545 LTILIYTLVLYEPLKYKDYTYQSGVYVFGWCLSAFGVGQVLFWAIPAVRKQPSHLGLWARIRKAF 609

  Fly   618 QPTAEWGPAGRPCVNLHAERYQSQNYDGVTN 648
            :|...|||:....:    :|||....:|..|
  Fly   610 EPLPNWGPSDPQTL----KRYQLFVQEGNAN 636

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	208/548 (38%)
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	196/504 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920