DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GlyT and CG13793

DIOPT Version :9

Sequence 1:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_609136.2	Gene:	CG13793 / 34047	FlyBaseID:	FBgn0031935	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	602	Identity:	151/602 - (25%)
Similarity:	262/602 - (43%)	Gaps:	86/602 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 RGTWTGRFDFLLSLLGYSVGL----GNVWRFPYLCYNNGGGAF-LIPFTIMLVIAGLPLMFMELS 116
            ||.|....|::.:..|.::.|    .:.|.|    :|.  |.| ::|:.:.:||..:|:|.:...
  Fly    12 RGNWEKPTDYIFACFGLALKLDIFVASFWFF----FNT--GIFGMVPYLMYMVIYLVPIMVIHSY 70

  Fly   117 FGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCE-- 179
            .||:::.|.::.: |..|||:|:|...:.::..:::||.:..|..:.::..||.|.||| :||
  Fly    71 MGQFSSSGFISAF-RLSPLFKGMGYVSLFLTITLLIYYTIFAAVPLLFVLNSFRPTLPW-SCEGF 133

  Fly   180 PAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLS 244
            .:|...   :.|:...|.||......:...|.|.....||         ..|:..||.:......
  Fly   134 KSWQND---TIAKWSICNATIAEEVAKETENDTYFYITNI---------HVPSVLYFKSHFESFQ 186

  Fly   245 KGIE-ETGSIKLSLAACLFLAWTIVFLCLCKGVQSS--GKVVYFTALFPYVVLVILFVRGVTLPG 306
            ...| ....|...|:....|.|..:.....|..:.:  ||.:.:..:....:|::.|||.:.|||
  Fly   187 NDSELNDYEISWHLSGLFALVWATIAFIFYKFSEPAKFGKCIRYMVIGTVALLLVCFVRFLFLPG 251

  Fly   307 ASTGILFYLTPDWKQLANAQVWGDA-----AVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIV 366
            |..|:..|:||..::.    |.|.:     |:|.|.|   .||.:|||||:|.|..|....|.|:
  Fly   252 AHLGLKNYMTPSIEEF----VVGTSSTFIMALQAFGA---GWGSVITLSSFNGFKTNIMSYSWII 309

  Fly   367 AFCNIATSFFAGLVIFSIIGFLAHELNVDVEK------VVDQGAGLAFIVYPEVVTRLPVSPVWA 425
            :|..|..     .::|.::.|:.....:.:.|      |::.  .:.|:.....::.|....:|.
  Fly   310 SFGQIFI-----YIMFGMVSFMLEHYFLGLPKPLFETQVINH--WVLFLSSASALSSLGWPNLWT 367

  Fly   426 VLFFVMLLTLGLDSQFALMETVTTAILDRFPNLRQYKIWVVLSVAIFGYIGGLG-----FTTNSG 485
            .:::.|||...|......:.|:..::.|.|..||..|..|.|     |.||||.     |.||.|
  Fly   368 FIYYTMLLMAALIVITTQIFTILQSLFDEFEQLRAKKQEVTL-----GLIGGLAVCSLYFCTNHG 427

  Fly   486 MYWLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPA 550
            :.:..:: ...|.:|..|:.:...:::.|:||..||..||:.|:|:....|..|   :.|::.|.
  Fly   428 VLYFAIL-SIDAIFSQTLLHLLLLLVVLWVYGRDRFQKDIKFMLGQPFASWKVF---ILRFVAPP 488

  Fly   551 TLLFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVIFLVAF----------QEIWRA-- 603
            ||:..|.   :|.|.....|.........:..|:..||:|.|....|          .|::||
  Fly   489 TLVICLV---LEIKMCLEEHSYSSSVLHFMAIILVGLPILAIPAYGFYYIHQRPGSISELFRATD 550

  Fly   604 --PMSLSFRDRIKHLLQ 618
              |:.:.:|.:...|:|
  Fly   551 WYPVEMEYRQQYGELVQ 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	145/581 (25%)
CG13793	NP_609136.2	SLC5-6-like_sbd	19..498	CDD:271356	132/524 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910