Protein Alignment GlyT and SLC6A19

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001003841.1
• Gene: SLC6A19 / 340024
• HGNCID: 27960
• Length: 634
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 229/633 - (36%)
• Similarity: 321/633 - (50%)
• Gaps: 126/633 - (19%)

  Fly    40 LDATGPGAGGAGESEHE----RGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFT 100
            |||..|........|.|    |..|..:..::|:.||:.|||||||||||||.::|||||:|||.
Human    11 LDARIPSLAELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFL 75

  Fly   101 IMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYM 165
            |:||:.|:||:::|.:.||....|.:.|:....|..:|||...:|.|.:|.||||.||:|.::|:
Human    76 ILLVLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYL 140

  Fly   166 FASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRP 230
            |.||...|||.:| |.                ..|.|.|:..|..::
Human   141 FNSFQEPLPWSDC-PL----------------NENQTGYVDECARSS------------------ 170

  Fly   231 PAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLV 295
            |.:.::....|.:|..|.::|||:..:..||..||:::::|..:|::::||.||.|:..|||||.
Human   171 PVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLT 235

  Fly   296 ILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCY 360
            |..:||:||.||:.||:|..||:..:||....|.||..|:||:.|.|:||||:.||||...|||.
Human   236 IFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCE 300

  Fly   361 KDSLIVAFCNIATSFFAGLVIFSIIGFLA---------------------HELNVDVEKVVD--- 401
            |||:||:..|..||.:..:|::|:|||.|                     .|.||..|..||
Human   301 KDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQ 365

  Fly   402 ----------------------------QGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLD 438
                                        :|.||||||:.|.:|::|:||:|:||||:||..|||.
Human   366 RCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLS 430

  Fly   439 SQFALMETVTTAILDRFPNLRQY-KIW--------VVLSVAIFGYIGGLGFTTNSGMYWLQLMDK 494
            |.|..||.|...:.|    ||.. ..|        :.|...:.|:|    ||.|||.|||.|:|.
Human   431 SMFGNMEGVVVPLQD----LRVIPPKWPKEVLTGLICLGTFLIGFI----FTLNSGQYWLSLLDS 487

  Fly   495 YAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFI-LFF 558
            ||.:..:|:||..|...:.::||..||..||:.|||.:.   |.||.:.||.::|..:|.| |||
Human   488 YAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKP---NIFWQVTWRVVSPLLMLIIFLFF 549

  Fly   559 NWVE---------YKPA-----KYGHYVYPMWADAVGWIVGLLPVLVI 592
            ..||         :.|.     |.....||.|...|..||..:|.|.|
Human   550 FVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTI 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	223/612 (36%)
SLC6A19	NP_001003841.1	SLC5-6-like_sbd	32..612	CDD:294310	223/612 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810