DRSC/TRiP Functional Genomics Resources

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Protein Alignment GlyT and Slc6a6

DIOPT Version :10

Sequence 1:NP_611836.2 Gene:GlyT / 37772 FlyBaseID:FBgn0034911 Length:1188 Species:Drosophila melanogaster
Sequence 2:XP_008761345.1 Gene:Slc6a6 / 29464 RGDID:61912 Length:631 Species:Rattus norvegicus


Alignment Length:591 Identity:248/591 - (41%)
Similarity:352/591 - (59%) Gaps:50/591 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    45 PGAGGAGESE---HERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIA 106
            ||.....|::   .:|..|:.:.||:||:.|..||||||||||||||.|||||||||:.|.|..:
  Rat    36 PGTRPEDEADGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGS 100

  Fly   107 GLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAP 171
            |||:.|:|:..|||.:.|.:..:.:.||||.|:|...|::.:::.:||.:|:||..:|:|.||..
  Rat   101 GLPVFFLEVIIGQYTSEGGITCWEKICPLFSGIGYASIVIVSLLNVYYIVILAWATYYLFQSFQK 165

  Fly   172 VLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYF 236
            .|||.:|..:|:|..|.     :.....|.::::     :.|||  |.|:         |..|::
  Rat   166 DLPWAHCNHSWNTPQCM-----EDTLRRNESHWV-----SLSAA--NFTS---------PVIEFW 209

  Fly   237 NNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRG 301
            ...||.||.||:..||:|..||.||.|.|.:.|.|:.|||:|:||||||||.||:.:|::|.|||
  Rat   210 ERNVLSLSSGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRG 274

  Fly   302 VTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIV 366
            :|||||..||.|||.|:..:|.:.|||.||..||||:.:...|.:.:|.||||:..|.|:|.:::
  Rat   275 LTLPGAGEGIKFYLYPNISRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLL 339

  Fly   367 AFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVM 431
            ...|..|||.:|..||||:||:|.|..||:..|.:.|.|||||.||:.||.:|:...|::|||:|
  Rat   340 GCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIM 404

  Fly   432 LLTLGLDSQFALMETVTTAILDRFPNL------RQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQ 490
            ||.|||||||..:|...|:::|.:|:.      |:..|.:|.|::   |:.||...|..|||..|
  Rat   405 LLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAIVCSIS---YLLGLTMVTEGGMYVFQ 466

  Fly   491 LMDKYAANWSVLL-IAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLF 554
            |.|.|||:...|| :|..||.:||||||.....:.|:.|||.|...|..:   .|..||||..:.
  Rat   467 LFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKY---SWAVITPALCVG 528

  Fly   555 ILFFNWVEYKPAKYGH-YVYPMWADAVGWIVGL-----LPVLVIFLVAFQEIWRAPMSLSFRDRI 613
            ...|:.|:|.|..|.. |.||.||..:||.:.|     :|::::.|:...|   .|:    |.||
  Rat   529 CFIFSLVKYVPLTYNKVYRYPDWAIGLGWGLALSSMVCIPLVIVILLCRTE---GPL----RVRI 586

  Fly   614 KHLLQP 619
            |:|:.|
  Rat   587 KYLITP 592

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GlyTNP_611836.2 SNF 57..597 CDD:395155 237/552 (43%)
Herpes_BLLF1 <884..1135 CDD:282904
Slc6a6XP_008761345.1 SLC5-6-like_sbd 51..592 CDD:444915 244/574 (43%)
Blue background indicates that the domain is not in the aligned region.

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