Protein Alignment GlyT and Slc6a18

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_058859.2
• Gene: Slc6a18 / 29323
• RGDID: 69352
• Length: 615
• Species: Rattus norvegicus
• Alignment Length: 649
• Identity: 227/649 - (34%)
• Similarity: 335/649 - (51%)
• Gaps: 126/649 - (19%)

  Fly    54 EHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFG 118
            |.||..|..:..:|||.:|::|||||:|||||||:.:||||||||:.|.||..|:||.::||:.|
  Rat    14 EDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCHTHGGGAFLIPYFIALVFEGIPLFYIELAIG 78

  Fly   119 QYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWS 183
            |....|.:.|::...|...|:|.|...||.:|.||||.|:.|.:::...||...|||..| |.
  Rat    79 QRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTILLWVLWFFLNSFQHPLPWSTC-PL-- 140

  Fly   184 TKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYF-NNFVLGLSKGI 247
                          ..|.|.:::.|.::.:.:                   || ....|.::..|
  Rat   141 --------------DLNRTGFVQECQSSGTVS-------------------YFWYRQTLNITSDI 172

  Fly   248 EETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGIL 312
            ..||:|:..|..||...||.|:||:.:|::|:|||:||||||||:||.|..:||:|||||:.|:.
  Rat   173 SNTGTIQWKLFLCLVACWTTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLT 237

  Fly   313 FYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFA 377
            :..||:.|.|.|.:||.|||.||||:||.|:||.|..:|||:..|||.||::.:|..|..||.:|
  Rat   238 YLFTPNMKILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNQPRNNCEKDAVTIALVNSMTSLYA 302

  Fly   378 GLVIFSIIGFLAH---------------------ELNVD-------------------------- 395
            .:.||||:||.|.                     ||::.
  Rat   303 SITIFSIMGFKASNDYGRCLDRNILSLINEFDFPELSISRDEYPSVLMYLNATQPERVARLPLKT 367

  Fly   396 --VEKVVDQ---GAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDR- 454
              :|..:|:   |.||||||:.|.|..:|.:.||:||||.||.||||.|.|..||.|.|.:.|.
  Rat   368 CHLEDFLDKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLFDMG 432

  Fly   455 -FPN--LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWIY 516
             .|.  .::....||..:.   ::..:.||..||.|||::.|.:||:.::::.|..|.:.:..:|
  Rat   433 ILPKGVPKETMTGVVCFIC---FLSAICFTLQSGSYWLEIFDSFAASLNLIIFAFMEVVGVIHVY 494

  Fly   517 GSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWV--------EYKP--AKYGHY 571
            |.:||.:||:.|.|:|.   :.:|.:.||.::| .|||.:|.:::        .||.  .:|.|:
  Rat   495 GIKRFCDDIEWMTGRRP---SLYWQVTWRVVSP-MLLFGIFLSYIVLLAQSSPSYKAWNPQYEHF 555

  Fly   572 ------VYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIK--HL---LQPTAEWG 624
                  :||.|......::..||.|.:..:|.     |.:...:|.|.|  ||   |:|....|
  Rat   556 PSREEKLYPGWVQVTCVLLSFLPSLWVPGIAL-----AQLLFQYRQRWKNTHLESALKPQESRG 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	216/618 (35%)
Slc6a18	NP_058859.2	SLC6sbd_B0AT3	16..591	CDD:212086	218/622 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810