Protein Alignment GlyT and Slc6a11

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_766478.1
• Gene: Slc6a11 / 243616
• MGIID: 95630
• Length: 627
• Species: Mus musculus
• Alignment Length: 629
• Identity: 260/629 - (41%)
• Similarity: 369/629 - (58%)
• Gaps: 73/629 - (11%)

  Fly    15 VGGGGGVVCPSTAISGCASGTALIQLDATGPGAGGAGESE----HERGTWTGRFDFLLSLLGYSV 75
            :|||||                         ||.|..|:.    ||||.|..:.:|:||:.|..:
Mouse    24 LGGGGG-------------------------GAAGTREARDKAVHERGHWNNKVEFVLSVAGEII 63

  Fly    76 GLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLG 140
            |||||||||||||.|||||||||:.:..:..|:|:.|:|.:.||:.:.|.:..:||.||||.|:|
Mouse    64 GLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIG 128

  Fly   141 TGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYL 205
            ....::.|.:.:||.:|:||.|||:...|...|||..|...|:|:.|..:      :..|.:.|.
Mouse   129 YATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEF------QKLNFSNYS 187

  Fly   206 R-TCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVF 269
            . :..||||                 |..|::...||.:|.|||..|:::..||.||..||||.:
Mouse   188 HVSLQNATS-----------------PVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICY 235

  Fly   270 LCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQ 334
            .|:.||.:|:|||||.||.|||::|:||.:|||||||||.||.|||.||..:|::.|||.||..|
Mouse   236 FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQ 300

  Fly   335 IFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKV 399
            |||:.:...|.|..|.|||.::||||:|.:::...|..|||.||..|||::||:|:|..|.:.:|
Mouse   301 IFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEV 365

  Fly   400 VDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPNL--RQY- 461
            .:.|.|||||.||:.||.:|:||:||.|||:||:.|||||||..:|::.||::|.:|.:  |.|
Mouse   366 AESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYR 430

  Fly   462 KIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLL-IAISECILIAWIYGSQRFLNDI 525
            :..::|:::|..|..||...|..|||..||.|.|||:...|| :||.||:.|.|:|||.||.::|
Mouse   431 RELLILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNI 495

  Fly   526 QGMIGKR-----SWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGH-YVYPMWADAVGWIV 584
            :.|||.|     .|        .|:.:||.....|..|..|:|||.||.: |.||.|...:||::
Mouse   496 EDMIGYRPLSLIKW--------CWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLM 552

  Fly   585 GLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAGR 628
            .|..:|.|.|..|.::|:...:|.  ::::.|..|:|:....|:
Mouse   553 ALSSMLCIPLWIFIKLWKTEGTLP--EKLQKLTVPSADLKMRGK 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	244/556 (44%)
Slc6a11	NP_766478.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		8/36 (22%)
		SLC6sbd_GAT3	44..585	CDD:212077	247/573 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000575
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820