Protein Alignment GlyT and Slc6a20b

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_035861.2
• Gene: Slc6a20b / 22599
• MGIID: 1336891
• Length: 635
• Species: Mus musculus
• Alignment Length: 644
• Identity: 225/644 - (34%)
• Similarity: 319/644 - (49%)
• Gaps: 141/644 - (21%)

  Fly    46 GAGGAGES---------------EHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAF 95
            ||||.|:.               |..|..|.....|||..:.|:|||||||||||||...|||:|
Mouse    22 GAGGPGQHPGRPRSTECAHPGVVEKVRPKWDNPLQFLLVCISYAVGLGNVWRFPYLCQMYGGGSF 86

  Fly    96 LIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAW 160
            |:|:.|||::.|:||:::||:.||....|.:..:|...|...|:|...::||.:..:|:|:|..|
Mouse    87 LVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGIASLVVSFLASVYFNVINTW 151

  Fly   161 TIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALG 225
            .::|:|.||...|||..| |..|                |.|.|...|..|:|.
Mouse   152 ALWYLFHSFQDPLPWSVC-PLNS----------------NHTGYDEECEKASST----------- 188

  Fly   226 ALKRPPAEEYF-NNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALF 289
                    :|| ....|.:|..|:|.|.::...|.||.|||.:|:||:.:|.:|:|||||||...
Mouse   189 --------QYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTTSL 245

  Fly   290 PYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNK 354
            ||.||:|..|||:||.||:.|:.:..||..:||||.:.|.:||.||||:|....||||..:|||:
Mouse   246 PYFVLIIYLVRGLTLHGATNGLAYMFTPKIEQLANPKAWINAATQIFFSLGLGCGGLIAFASYNE 310

  Fly   355 FSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLA------------------------------ 389
            .||:|.|.:|||:..|..|:.|:.:|.|||.||.|
Mouse   311 PSNDCQKHALIVSVINSTTAIFSSIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTVSN 375

  Fly   390 ---------------------HELNVDVEKVVD---QGAGLAFIVYPEVVTRLPVSPVWAVLFFV 430
                                 |..|..:|..:|   ||.|||||||.|.:..:.||.:|:||:|.
Mouse   376 LEEVKNYLASTYPNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFF 440

  Fly   431 MLLTLGLDSQFALMETVTTAILDR------FPNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWL 489
            ||||||:.|.......:.|.:.|.      .|......:..:|:.||     |:.||..:|.||.
Mouse   441 MLLTLGMGSMVGTGTAILTPLTDSKIISSYLPKEAISGLVCLLNCAI-----GMVFTMEAGNYWF 500

  Fly   490 QLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKR-SWFWNFFWGIMWRYITPATL- 552
            .|.:.|.|..|:|||.:.|.|.:.::||.:||.:|::.|.|:. ||:|.    :||.:::|..:
Mouse   501 DLFNDYTATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWK----VMWAFVSPLLIV 561

  Fly   553 -LFILFFN------WVEYK--PAKYGHYV---YPMWADAVGWIVGLL---PVLVIFLVA 596
             |||.:.:      .::|:  .|..||.|   ||.:|.||   :|||   ..:.|.|||
Mouse   562 GLFIFYLSDYILTGTLQYQAWDATQGHVVTKDYPTYALAV---IGLLVASSTMCIPLVA 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	219/618 (35%)
Slc6a20b	NP_035861.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		5/15 (33%)
		SLC5-6-like_sbd	45..620	CDD:294310	220/621 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810