Protein Alignment GlyT and Slc6a18

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001035782.1
• Gene: Slc6a18 / 22598
• MGIID: 1336892
• Length: 615
• Species: Mus musculus
• Alignment Length: 627
• Identity: 220/627 - (35%)
• Similarity: 326/627 - (51%)
• Gaps: 117/627 - (18%)

  Fly    54 EHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFG 118
            |.||..|..:..:|||.:|::|||||:|||||||..:||||||||:.|.||..|:||.::||:.|
Mouse    14 EDERPKWDNKLQYLLSCIGFAVGLGNIWRFPYLCQTHGGGAFLIPYFIALVFEGIPLFYIELAIG 78

  Fly   119 QYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWS 183
            |....|.:.|::...|...|:|.|...||.:|.||||.::.|.:::...||...|||..| |.
Mouse    79 QRLRRGSIGVWKTISPYLGGVGLGCFSVSFLVSLYYNTVLLWVLWFFLNSFQHPLPWSTC-PL-- 140

  Fly   184 TKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYF-NNFVLGLSKGI 247
                          ..|.|.:::.|.::.:.:                   || ....|.::..|
Mouse   141 --------------DLNRTGFVQECQSSGTVS-------------------YFWYRQTLNITSDI 172

  Fly   248 EETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGIL 312
            ..||:|:..|..||...|:.|:||:.:|::|:|||:||||||||:||.|..:||:|||||:.|::
Mouse   173 SNTGTIQWKLFLCLVACWSTVYLCVIRGIESTGKVIYFTALFPYLVLTIFLIRGLTLPGATEGLI 237

  Fly   313 FYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFA 377
            :..||:.|.|.|.:||.|||.||||:||.|:||.|..:|||...|||.||::|:|..|..||.:|
Mouse   238 YLFTPNMKTLQNPRVWLDAATQIFFSLSLAFGGHIAFASYNPPRNNCEKDAVIIALVNSMTSLYA 302

  Fly   378 GLVIFSIIGFLAH---------------------ELNVD-------------------------- 395
            .:.|||::||.|.                     ||::.
Mouse   303 SIAIFSVMGFKASNDYGRCLDRNILSLINEFDLPELSISRDEYPSVLMYLNATQTARVAQLPLKT 367

  Fly   396 --VEKVVDQ---GAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRF 455
              :|..:|:   |.||||||:.|.|..:|.:.||:||||.||.||||.|.|..||.|.|.:||..
Mouse   368 CHLEDFLDKSASGPGLAFIVFTEAVLHMPGASVWSVLFFGMLFTLGLSSMFGNMEGVITPLLDMG 432

  Fly   456 PNLRQYKIWVVLSVAIFG-YIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWIYGSQ 519
            ...:.....|:..|..|. ::..:.||..||.|||::.|.:||:.::::.|..|.:.:..|||.:
Mouse   433 ILPKGIPKEVMTGVICFACFLSAICFTLQSGGYWLEIFDSFAASLNLIIFAFMEVVGVIHIYGMK 497

  Fly   520 RFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWV--------EYKP--AKYGHY--- 571
            ||.:||:.|.|:|.   ..:|.:.||.::| .|||.:|.:::        .||.  .:|.|:
Mouse   498 RFCDDIEWMTGRRP---GLYWQVTWRVVSP-MLLFGIFLSYIVLLIQTPPSYKAWNPQYEHFPSR 558

  Fly   572 ---VYPMWADAVGWIVGLLPVLVI-------FLVAFQEIWRA 603
               .||.|......::..||.|.:       .|..:::.|:|
Mouse   559 EEKFYPGWVQVTCVLLSFLPSLWVPGVALAQLLSQYKQRWKA 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	217/622 (35%)
Slc6a18	NP_001035782.1	SLC6sbd_B0AT3	16..591	CDD:212086	216/614 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810