Protein Alignment GlyT and Slc6a13

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_006237280.2
• Gene: Slc6a13 / 171163
• RGDID: 620788
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 244/598 - (40%)
• Similarity: 351/598 - (58%)
• Gaps: 66/598 - (11%)

  Fly    56 ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQY 120
            ||..||.:.:|:||:.|..:|||||||||||||.||||||.||:.|.|...|:|:.|:|.:.|||
  Rat    31 EREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQY 95

  Fly   121 AALGPVAVYRRFCPLFR------GLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCE 179
            ...|.:..:|:.||:|.      |:|....::.:::.:||.:::||.:||:|:||...|||.:|.
  Rat    96 TNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNVYYIVVLAWALFYLFSSFTTDLPWGSCS 160

  Fly   180 PAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLS 244
            ..|:|:.|..:      :.||.:..: |..||||                 |..|::...||.:|
  Rat   161 HEWNTENCVEF------QKTNNSLNV-TSENATS-----------------PVIEFWERRVLKIS 201

  Fly   245 KGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGAST 309
            .||:..||::..|..||.|||.|.:.|:.|||:|:||||||||.|||::||:|.:||||||||:.
  Rat   202 DGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGAAQ 266

  Fly   310 GILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATS 374
            ||.|||.|:..:|.:.|||.||..||||:.:...|.|..|.||||:.||||:|.:.:...|.:||
  Rat   267 GIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCVALCILNSSTS 331

  Fly   375 FFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDS 439
            |.||..||||:||::.|..|.:.:|.:.|.|||||.||..|..||.||:||..||.|::.|||||
  Rat   332 FVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDS 396

  Fly   440 QFALMETVTTAILDRFP------NLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAAN 498
            ||..:|::.||::|.:|      |.|:.   ::|.|::..:..||...|..|||..||.|.|||:
  Rat   397 QFVCVESLVTALVDMYPRVFRKKNRREI---LILIVSVVSFFIGLIMLTEGGMYVFQLFDYYAAS 458

  Fly   499 WSVLL-IAISECILIAWIYGSQRFLNDIQGMIGKRSW-----FWNFFWGIMWRYITPATLLFILF 557
            ...|| :||.|.:.:||:||:.||.::|:.|||.:.|     .|.||        |||..|....
  Rat   459 GMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFF--------TPAVCLATFL 515

  Fly   558 FNWVEYKPAKYG-HYVYPMWADAVGWIVGL-----LPVLVIFLVAFQEIWRAPMSLSFRDRIKHL 616
            |:.::|.|..|. .|.||.|.||:||::.|     :|...|:.:   ...:.|:    |:|::.|
  Rat   516 FSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSIYKL---RTLKGPL----RERLRQL 573

  Fly   617 LQPTAEWGPAGRP 629
            :.|..:.....:|
  Rat   574 VCPAEDLPQKSQP 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	237/563 (42%)
		Herpes_BLLF1	<884..1135	CDD:282904
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:444915	242/590 (41%)