Protein Alignment GlyT and DAT

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_061499264.1
• Gene: DAT / 1269812
• VectorBaseID: AGAMI1_006978
• Length: 678
• Species: Anopheles gambiae
• Alignment Length: 646
• Identity: 278/646 - (43%)
• Similarity: 394/646 - (60%)
• Gaps: 49/646 - (7%)

  Fly     4 SSKSGSAGVGG-----VGGGGGVVCPSTAISGCASGTALIQL-----------------DATGPG 46
            ||||||..:.|     :.||.     ...:.|.:.||||...                 .|.|.|
Mosquito    23 SSKSGSDSIEGDALKELNGGA-----ENGVGGDSEGTALAMTTIGQIKAKGRPGLLPRNGAGGGG 82

  Fly    47 AGGAGESE--HERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLP 109
            .||.||.:  .||.||:|:.|||||::|::|.|.||||||||||.|||||||||:.||||:.|:|
Mosquito    83 GGGGGELDDGEERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYGIMLVVGGIP 147

  Fly   110 LMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLP 174
            |.:|||:.||:...|.:..:.|..|||:|:|..::|::..|..|||:||||::.:.||||...||
Mosquito   148 LFYMELALGQFNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTDSLP 212

  Fly   175 WQNCEPAWSTKYC--FSYAQADQCEATNGTYYLRTCHNATSAAEN-NITTLALGALKRPPAEEYF 236
            |.:|..||:|..|  |.|..:......|.|..|..  |.|..... |.|..|      ..|.|||
Mosquito   213 WTHCSNAWNTVECKPFGYINSTAATVVNRTGVLAA--NVTGTVSTINDTKFA------SAASEYF 269

  Fly   237 NNFVLGL--SKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFV 299
            |.::|.|  |:||.:.|:||..:|.||...:.|.:..|.||:.:|||||:|||||||.||:||.|
Mosquito   270 NRYILELDKSEGIHDLGAIKWDMALCLLAVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLV 334

  Fly   300 RGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSL 364
            ||:||||::.|||:||.|::..:.||:||.|||.|:||:|.|.:|.|:..:||||:.||.|||:|
Mosquito   335 RGITLPGSAEGILYYLRPNFDVIYNAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDAL 399

  Fly   365 IVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFF 429
            :.:..|.||||.||.||||::|::||.....::.|..:|.||.|:|||..:..:|.|..||::||
Mosquito   400 LTSLINSATSFIAGFVIFSVLGYMAHASGQSIQDVATEGPGLVFVVYPAAIATMPGSIFWALIFF 464

  Fly   430 VMLLTLGLDSQFALMETVTTAILDRFPNL-RQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMD 493
            :|||||||||.|...|.:.||:.|.||.: |..:|:|.:..::: ::.||...|..|.|:.||:|
Mosquito   465 MMLLTLGLDSSFGGSEAIITALSDEFPKIGRNREIFVAVLFSLY-FVVGLASCTQGGFYFFQLLD 528

  Fly   494 KYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFF 558
            :|||.:|:|:....|.|.::||||::||.|||:.|||   :....:|.:.|:::.|..||||:.:
Mosquito   529 RYAAGYSILIAVFFEAIAVSWIYGTERFCNDIKDMIG---FAPGIYWRVCWKFVAPLFLLFIIIY 590

  Fly   559 NWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQP 619
            ..:.::|..|..||||.||:.:||.:....:::|.|:|..::...|.||  |.|.|.|..|
Mosquito   591 GLIGHEPLSYEDYVYPSWANVLGWCIAGSSMIMIPLMASYKLIVTPGSL--RQRFKILTTP 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	247/545 (45%)
		Herpes_BLLF1	<884..1135	CDD:282904
DAT	XP_061499264.1	None