Protein Alignment GlyT and Slc6a9

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_006238687.1
• Gene: Slc6a9 / 116509
• RGDID: 621243
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 288/598 - (48%)
• Similarity: 400/598 - (66%)
• Gaps: 33/598 - (5%)

  Fly    43 TGPGAGGAGESEH-------ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFT 100
            :.|...||..||.       .||.|..:.:|:|:.:||:||||||||||||||.||||||:.|:.
  Rat    11 SSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYF 75

  Fly   101 IMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYM 165
            ||||..|:||.||||||||:|:.|.:.|: |..|:|:|:|.||::||..:.:|||::|....:|.
  Rat    76 IMLVFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYF 139

  Fly   166 FASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKR- 229
            |:|...||||..|...|:|..|...  .|....|||        :..:|...|::.|....|:|
  Rat   140 FSSMTHVLPWAYCNNPWNTPDCAGV--LDASNLTNG--------SRPTALSGNLSHLFNYTLQRT 194

  Fly   230 PPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVL 294
            .|:|||:..:||.||..|.:.|.::|.|..||.::|.:|||||.:||:||||||||||.||||||
  Rat   195 SPSEEYWRLYVLKLSDDIGDFGEVRLPLLGCLGVSWVVVFLCLIRGVKSSGKVVYFTATFPYVVL 259

  Fly   295 VILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNC 359
            .|||||||||.||.|||::||||.|.::..|:||||||.|||::|..|||||||::|||||.|||
  Rat   260 TILFVRGVTLEGAFTGIMYYLTPKWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNC 324

  Fly   360 YKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVW 424
            |:||:|::..|.|||.:||.|||||:||:|:.|.|||.:|.|.|.||||:.|||.:|.||:||:|
  Rat   325 YRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLW 389

  Fly   425 AVLFFVMLLTLGLDSQFALMETVTTAILDRFPN--LRQYKIWVVLSVAIFGYIGGLGFTTNSGMY 487
            ::|||.||:.|||.:||.|:||:.|||:|...|  :.|.|.:|.|.||:.|::.|:..|:.:|:|
  Rat   390 SLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIY 454

  Fly   488 WLQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNF----FWGIMWRYIT 548
            ||.|||.|||::|:::|:...|:.|.:|||.:.:..|||.|:|       |    |:.|.||:::
  Rat   455 WLLLMDNYAASFSLVVISCIMCVSIMYIYGHRNYFQDIQMMLG-------FPPPLFFQICWRFVS 512

  Fly   549 PATLLFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRI 613
            |..:.|||.|..::|:|..|.||.||.||.|:|:::.|..|:.|.|.|..::.|.... :...|:
  Rat   513 PTIIFFILIFTVIQYRPITYNHYQYPGWAVAIGFLMALSSVICIPLYALFQLCRTDGD-TLLQRL 576

  Fly   614 KHLLQPTAEWGPA 626
            |:..:|:.:||||
  Rat   577 KNATKPSRDWGPA 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	274/546 (50%)
		Herpes_BLLF1	<884..1135	CDD:282904
Slc6a9	XP_006238687.1	SLC6sbd_GlyT1	16..599	CDD:212067	287/593 (48%)