Protein Alignment GlyT and slc6a6

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_017949178.2
• Gene: slc6a6 / 100494063
• XenbaseID: XB-GENE-991256
• Length: 616
• Species: Xenopus tropicalis
• Alignment Length: 602
• Identity: 252/602 - (41%)
• Similarity: 362/602 - (60%)
• Gaps: 40/602 - (6%)

  Fly    45 PGAGGAGESE---HERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIA 106
            ||.....|::   .:|..|..:.||:||:.|..:|||||||||||||.|||||||||:.|.|...
 Frog    26 PGTRPEDEADGKPPQREKWASKIDFVLSVAGGFIGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGG 90

  Fly   107 GLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAP 171
            |||:.|:|:..||:.:.|.:..:.:.||:|.|:|...|::.:::.:||.:|:||.::|:|.||..
 Frog    91 GLPVFFLEVVLGQFTSEGGITCWEKICPVFTGIGYASIVIVSLLNVYYIVILAWGVYYLFQSFQG 155

  Fly   172 VLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYF 236
            .|||..|...|:|:.|     .:.....|.|.::       |....|.|:         |..|::
 Frog   156 QLPWALCHQPWNTESC-----VEDTFRKNWTMWM-------SMNSTNFTS---------PVTEFW 199

  Fly   237 NNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRG 301
            .:.||.|||||::.|.:|..||.||.|.|.|.|.|:.|||:|:||||||||.||:::|::|.:||
 Frog   200 EHKVLSLSKGIDDVGVLKWDLALCLLLTWVICFFCIWKGVRSTGKVVYFTATFPFIMLLVLLIRG 264

  Fly   302 VTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIV 366
            ||||||:.||.|||.||..:||:.|||.||..||||:.:...|.:.:|.||||:..|||:|.:::
 Frog   265 VTLPGAAEGIKFYLYPDITRLADPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLL 329

  Fly   367 AFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVM 431
            ...|..|||.:|..|||::||:|.|..||:..|.:.|.|||||.||:.|:.:|:...||:|||:|
 Frog   330 GCLNSGTSFVSGFAIFSVLGFMAQEQGVDIADVAESGPGLAFIAYPKAVSMMPLPSFWAILFFIM 394

  Fly   432 LLTLGLDSQFALMETVTTAILDRFPN-LRQ-YKIWVVLSVAIF-GYIGGLGFTTNSGMYWLQLMD 493
            ||.|||||||..:|...|:::|.:|: ||: |:..:.::|..| .|:.||...|..|||..||.|
 Frog   395 LLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAVVCFLSYLLGLTMVTEGGMYVFQLFD 459

  Fly   494 KYAANWSVLL-IAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILF 557
            .|||:...|| :|..||:.:||:||:.:|.::|:.|||.:...| ..|.  |..|||...:....
 Frog   460 YYAASGVCLLWVAFFECVAVAWVYGADKFYDNIEDMIGYKPGPW-MKWS--WTVITPLLCVACFI 521

  Fly   558 FNWVEYKPAKYG-HYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPT- 620
            |:..:|.|..|. :||||.||..:||::.|..::.|.||....|.|:..||.  :|||.:..|.
 Frog   522 FSLAKYTPLTYNKYYVYPDWAIGLGWVLALSSMICIPLVVVFHIVRSDGSLI--ERIKAVTAPRE 584

  Fly   621 ----AEWGPAGRP-CVN 632
                |:...|..| |.|
 Frog   585 VNRWAKDSEAAAPICTN 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	237/550 (43%)
slc6a6	XP_017949178.2	SLC6sbd_TauT	41..582	CDD:271398	243/566 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920