Protein Alignment GlyT and slc6a12

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_031754510.1
• Gene: slc6a12 / 100492029
• XenbaseID: XB-GENE-6033368
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 272/653 - (41%)
• Similarity: 385/653 - (58%)
• Gaps: 82/653 - (12%)

  Fly    46 GAGGA------GESEH------ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIP 98
            ||||:      ||..|      :||.|:.:.:|:||:.|..:|||||||||||||.||||||.||
 Frog    12 GAGGSDTLCALGEGRHREPEIEDRGQWSNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIP 76

  Fly    99 FTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIF 163
            :.|.|...|:|:.|:|.:.|||.:.|.:..:|:.||||.|:|....::...:.:||.:|:||.:|
 Frog    77 YLIFLFTCGIPVFFLETALGQYTSQGGITAWRKICPLFEGIGYASQVIEGYLNIYYIVILAWALF 141

  Fly   164 YMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALK 228
            |:|:||...|||..|...|:|::|..:....:              |.|| .||:.:::.
 Frog   142 YLFSSFTAELPWATCNNTWNTEHCIDFVGKSE--------------NFTS-LENSTSSVV----- 186

  Fly   229 RPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVV 293
                 |::...||.||:|||..|:::..||.||.|||.|.:.|:.|||:|:||||||||.||||:
 Frog   187 -----EFWERRVLHLSEGIEHLGNVRWDLALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYVM 246

  Fly   294 LVILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNN 358
            |:||.|||||||||..||:|||.||..:|.:.|||.||..||||:.:...|.|..|.||||::||
 Frog   247 LIILLVRGVTLPGAYEGIIFYLKPDMTRLQDPQVWMDAGTQIFFSYAICQGCLTALGSYNKYNNN 311

  Fly   359 CYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPV 423
            ||:|.:.:.|.|..|||.||..|||::||:|.|..|.:.:|.:.|.|||||.||:.||.:||||:
 Frog   312 CYRDCIALCFLNSITSFVAGFAIFSVLGFMAQEQGVPISEVAESGPGLAFIAYPKAVTMMPVSPL 376

  Fly   424 WAVLFFVMLLTLGLDSQFALMETVTTAILDRFPNLRQYKI---WVVLSVAIFGYIGGLGFTTNSG 485
            |:.|||:||:.|||||||..:|::.|||:|.||::.:.|.   :.:|:||:..|:.||...|..|
 Frog   377 WSCLFFLMLIFLGLDSQFVCVESLVTAIVDMFPHVFRKKYRREFFILAVAVICYLLGLILLTEGG 441

  Fly   486 MYWLQLMDKYAANWSVLL-IAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITP 549
            ||..||.|.|||:.:.|| :||.|.|.:.::||:.||.::|:.|||.|.|....:   .|.:.||
 Frog   442 MYVFQLFDYYAASGTCLLFVAIFEVICVGYVYGANRFYDNIEDMIGYRPWPLVKY---CWLFATP 503

  Fly   550 ATLLFILFFNWVEYKPAKYGH-YVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRI 613
            |..|....|:.::|.|.||.: ||||.|..|:||::.|..::.|.:.||..|.|.  ..||..|:
 Frog   504 AVCLGTFLFSLIKYSPLKYNNRYVYPSWGYAIGWLMALSSMICIPIYAFYIILRT--KGSFTQRL 566

  Fly   614 KHLLQPTAEWGPAGRPCVNLHAERYQSQNYDGVTNTKILIEEEASPKQ------------AANKK 666
            |.|:.|              |.:..|.:.|         :::.|.|||            ..:||
 Frog   567 KQLVTP--------------HTDLPQPKKY---------LKDRADPKQIEVLGLEAKDGLIVSKK 608

  Fly   667 DRQ 669
            :.|
 Frog   609 ETQ 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	245/544 (45%)
		Herpes_BLLF1	<884..1135	CDD:282904
slc6a12	XP_031754510.1	SLC5-6-like_sbd	34..572	CDD:444915	254/567 (45%)