DRSC/TRiP Functional Genomics Resources

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Protein Alignment GlyT and slc6a8

DIOPT Version :10

Sequence 1:NP_611836.2 Gene:GlyT / 37772 FlyBaseID:FBgn0034911 Length:1188 Species:Drosophila melanogaster
Sequence 2:XP_002935539.1 Gene:slc6a8 / 100489909 XenbaseID:XB-GENE-986840 Length:644 Species:Xenopus tropicalis


Alignment Length:613 Identity:262/613 - (42%)
Similarity:373/613 - (60%) Gaps:41/613 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQY 120
            ||.|||.:.||::|.:|::||||||||||||||.||||.||||:.::.::.|:|:.|:|::.||:
 Frog    57 ERDTWTSQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILIAILGGIPIFFLEIALGQF 121

  Fly   121 AALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTK 185
            ...|.:||: ...|||:|:|...:::......||.||:.|.::|:..||:.||||.:|...|::.
 Frog   122 MKAGSIAVW-NIAPLFQGIGFASVVIVFFCNTYYILILTWGVYYLVKSFSAVLPWSHCNNTWNSP 185

  Fly   186 YCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKGIEET 250
            .|....:.:.|  ||||         .::...|:|...| |.|..|..|::...||.||.|:::.
 Frog   186 DCVDIFRQEDC--TNGT---------ANSTFGNLTCNEL-ADKVSPITEFWEKKVLRLSSGLDDI 238

  Fly   251 GSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYL 315
            |||...|..||...|.:|:.|:.|||:|:||:|||||.||||||:||.|||..||||:.||::||
 Frog   239 GSINWELLLCLIGCWLLVYFCVWKGVKSTGKIVYFTATFPYVVLLILLVRGAMLPGATEGIIYYL 303

  Fly   316 TPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLV 380
            .|||.:|..||||.||..||||:.:...|.|..|.|||:|:|:||||:.|:|..|..||||||.|
 Frog   304 KPDWSKLGTAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFILAVINSGTSFFAGFV 368

  Fly   381 IFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALME 445
            :|||:||:|:|..||:.||.:.|.|||||.||..|:.:||:|:|:.|||.|||.|||||||..:|
 Frog   369 VFSILGFMANEQGVDISKVAESGPGLAFIAYPRAVSLMPVAPLWSALFFFMLLLLGLDSQFVGVE 433

  Fly   446 TVTTAILDRFPNLRQYKIWVVLSVAI---FGYIGGLGFTTNSGMYWLQLMDKYAANWSVLL-IAI 506
            .:.|||||..|....::....::|||   ..::..|...|..|||..||.|.|:|:...|| ...
 Frog   434 GLITAILDLLPARYYFRFQREIAVAICCAIMFLIDLSMLTEGGMYVFQLFDYYSASGMTLLWQTF 498

  Fly   507 SECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGH- 570
            .:|:::||:||:.||::||..|||.|.:.| ..|  .|.::||...:.|..||.:.|||..|.: 
 Frog   499 WQCVVVAWVYGADRFMDDIARMIGYRPFPW-MKW--CWSFVTPFVCMAIFLFNLINYKPLTYNNS 560

  Fly   571 YVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPAGRPCVNLHA 635
            |.||.|.:|:||...|..:|.:.:....:|..|..||  |:|.:||.:|.  ||        .|.
 Frog   561 YTYPWWGEAIGWGFALSSMLCVPVTFLYKITCAKGSL--RERWQHLTKPI--WG--------AHH 613

  Fly   636 ERYQSQNYD--------GVTNTKILIEE 655
            ..|.:.:.|        .|::.:::|.|
 Frog   614 LEYMAPDPDVKSLTTLTPVSDNRVIIFE 641

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GlyTNP_611836.2 SNF 57..597 CDD:395155 244/544 (45%)
Herpes_BLLF1 <884..1135 CDD:282904
slc6a8XP_002935539.1 SLC5-6-like_sbd 58..644 CDD:444915 261/612 (43%)
Blue background indicates that the domain is not in the aligned region.

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