Protein Alignment GlyT and slc6a3

DIOPT Version :9

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_002933174.1
• Gene: slc6a3 / 100488824
• XenbaseID: XB-GENE-982873
• Length: 621
• Species: Xenopus tropicalis
• Alignment Length: 574
• Identity: 247/574 - (43%)
• Similarity: 356/574 - (62%)
• Gaps: 36/574 - (6%)

  Fly    56 ERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQY 120
            ||.||:.:.|||||::|::|.|.||||||||||.|||||||:|:...:||||:||.:|||:.||:
 Frog    59 ERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYIFFMVIAGMPLFYMELALGQF 123

  Fly   121 AALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTK 185
            ...|...|: :.||:|:|:|..:||:|..|..:||:||||.:.|:|:||...|||.:|..:|::.
 Frog   124 NREGAAGVW-KICPIFKGVGYTVILISLYVGFFYNVIIAWALQYLFSSFTSELPWIHCNNSWNSP 187

  Fly   186 YCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGAL----KRPPAEEYFNNFVLGL--S 244
            .|            :.|.|            :|.:..:|..|    |..||.|||...||.|  |
 Frog   188 NC------------SETKY------------SNFSDYSLFGLNDTYKVTPAAEYFERGVLHLHES 228

  Fly   245 KGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGAST 309
            :||.:.||.:..|.:||.:....::..|.|||::|||||:.||..|||||..|.:||||||||..
 Frog   229 QGIHDLGSPRWKLTSCLIVVIVFLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAID 293

  Fly   310 GILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATS 374
            ||..||:.|:.:|..|.||.|||.||.|:|...:|.||..||||||:||||:|::|....|..||
 Frog   294 GIKAYLSVDFLRLCEASVWIDAATQICFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSVNSLTS 358

  Fly   375 FFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDS 439
            ||:|.||||.:|::|.:.||.:..|...|.||.||:|||.:..||:|.||:|:||:||||||:||
 Frog   359 FFSGFVIFSFLGYMAQKHNVPIGDVAKDGPGLIFIIYPEAIATLPLSSVWSVIFFIMLLTLGIDS 423

  Fly   440 QFALMETVTTAILDRFPNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLI 504
            ....||:|.|.::|.|..||:::....|.:.:..:...|...||.|:|...|:|.:||..|:|..
 Frog   424 AMGGMESVITGLIDEFKFLRRHRELFTLFIVLCTFFTSLSCVTNGGIYVFTLLDHFAAGTSILFG 488

  Fly   505 AISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYG 569
            .:.|.|.|||.||..||.:||:.|||||.   ..:|.:.|::::|..|||::..:.|.|:..|||
 Frog   489 VLIEAIGIAWFYGVGRFSDDIEEMIGKRP---GLYWRLCWKFVSPCFLLFVVVVSIVTYRSPKYG 550

  Fly   570 HYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEW 623
            :|.:|.||:.:||:|.:..:.::.|.|..:.  :.:..|||::|.:.:.|..|:
 Frog   551 NYTFPEWANVIGWLVAISSMAMVPLYAIYKF--SSLHGSFREKIAYAITPEKEY 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	240/551 (44%)
slc6a3	XP_002933174.1	SLC6sbd_DAT1	60..615	CDD:212083	246/573 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010