Protein Alignment GlyT and slc6a18

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001108369.2
• Gene: slc6a18 / 100141332
• ZFINID: ZDB-GENE-080219-9
• Length: 618
• Species: Danio rerio
• Alignment Length: 674
• Identity: 240/674 - (35%)
• Similarity: 334/674 - (49%)
• Gaps: 145/674 - (21%)

  Fly    53 SEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSF 117
            |..||..|..:..:||:.:|::|||||:|||||||...||||||||:.|.||..||||:::||:.
Zfish     9 SVQERPKWDNKVQYLLTCVGFAVGLGNIWRFPYLCQIYGGGAFLIPYLIALVFEGLPLLYLELAI 73

  Fly   118 GQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAW 182
            ||....|.:.|:....||..|:|...::||.:|.|:||.|:||.::|.|.||...|||..| |.
Zfish    74 GQSLRKGSIGVWHSISPLLGGVGVASMVVSFLVGLFYNTILAWVLWYFFHSFEDPLPWSQC-PI- 136

  Fly   183 STKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKGI 247
                      .|..|.     |:..|.::|                  |...|:....|.:|..|
Zfish   137 ----------NDNLEG-----YVEECVSST------------------PVNYYWYRQTLNISPDI 168

  Fly   248 EETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGIL 312
            |::||::.:|..||..||:||::|..:|:::.||.||.||.|||:||.|..||.:|||||:.|:.
Zfish   169 EQSGSLQWTLVLCLATAWSIVYICFIRGIETIGKAVYVTATFPYLVLTIFLVRALTLPGATDGLQ 233

  Fly   313 FYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFA 377
            :..||||..|.|.|||.|||.||||:||.|:||||..||||...|:|.:|:|.|...|.|||.:|
Zfish   234 YLFTPDWSLLTNPQVWLDAATQIFFSLSLAFGGLIAFSSYNPKKNDCERDALFVGIINSATSLYA 298

  Fly   378 GLVIFSIIGFLA-----------------------------------HELNV-DVEKV------- 399
            .:.||:|:||.|                                   .:||. |.::|
Zfish   299 SIPIFAILGFKATSNFNSCVNSNILDLTNAFDIGDRNITIENYDSWLRDLNASDPDRVSSLNLKH 363

  Fly   400 ------VDQ---GAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILD-- 453
                  :||   |.||||||:.|.|..:|.|.||||||||||.:|||.|.|..:|.|.|.:||
Zfish   364 CVLKNFLDQSASGTGLAFIVFTEAVIEMPGSQVWAVLFFVMLFSLGLSSMFGNLEGVLTPLLDLH 428

  Fly   454 RFPNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISECILIAWIYGS 518
            ..|.....:|:..| :.:..::..|.||..||.|||::.:.|..:..:|:||..|.|.:...||.
Zfish   429 MVPRWMPKEIFTGL-ICVVNFLVALIFTLGSGNYWLEIFNSYVGSVPLLVIAFFEIIAVVCFYGI 492

  Fly   519 QRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILF----------------------FNWV 561
            :||.:||:.|.|:|.   |.||...|..|:|..||.:|.                      |...
Zfish   493 KRFSDDIEQMTGRRP---NLFWRCCWMGISPVMLLVVLVAYVVVQVQKHPTYPAWNPQYENFPET 554

  Fly   562 EYKPAKYGHYVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPA 626
            |.||       |..|..::..::..:||:.|.:||...:.|       |....|          :
Zfish   555 EEKP-------YSTWVFSICVLLSSVPVISIPIVALYRLMR-------RHTHPH----------S 595

  Fly   627 GRPCVNLHAERYQSQNYDGVTNTK 650
            |.|      ..|.:|:|...|:|:
Zfish   596 GYP------NPYTNQSYTDDTHTQ 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	227/615 (37%)
		Herpes_BLLF1	<884..1135	CDD:282904
slc6a18	NP_001108369.2	None