Protein Alignment GlyT and slc6a8l

DIOPT Version :10

• Sequence 1: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_012815966.1
• Gene: slc6a8l / 100127575
• XenbaseID: XB-GENE-5768780
• Length: 654
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 269/639 - (42%)
• Similarity: 368/639 - (57%)
• Gaps: 51/639 - (7%)

  Fly     4 SSKSGSAGVGGVGG----GGGVVCPSTAISGCASGTALIQLDATGPGAGGAGESEHERGTWTGRF 64
            :.|.|.:|...:.|    |||...|..        .|:| .....|..|.......||.|||.:.
 Frog    13 TEKPGCSGAPDMEGAETVGGGEAVPDE--------KAVI-APLVVPSMGQVKIPIPERETWTRQM 68

  Fly    65 DFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVY 129
            ||::|.:|::||||||||||||||.||||.||||:.:::.:.|:|:.|:|::.||:...|.:|.:
 Frog    69 DFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFLEIALGQFMKQGGIAAW 133

  Fly   130 RRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQAD 194
             ...|||:|||...:::......||.:|:.|.::|:..||...|||..|...|::|.|......|
 Frog   134 -NIAPLFKGLGFASMVIVFFCNTYYIMILVWGLYYLVHSFTNTLPWATCGNPWNSKECTEVFLVD 197

  Fly   195 QCEATNGTYYLRTCHNATSAAENNITTLALGAL--KRPPAEEYFNNFVLGLSKGIEETGSIKLSL 257
            .|  .||     :..|.|.:  ..:..::..||  ||.|..|::...||.:|.|:.|.|.:...:
 Frog   198 HC--NNG-----SLANVTDS--GTLVNISCDALVNKRSPVIEFWERKVLQISGGLNEPGQLNWQM 253

  Fly   258 AACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLTPDWKQL 322
            ..||...|.||:.|:.|||:|:|||||||||||||||::|...|||||||..||::||.|:|.:|
 Frog   254 ILCLMATWVIVYFCIWKGVKSTGKVVYFTALFPYVVLIVLLAHGVTLPGALDGIVYYLKPNWSKL 318

  Fly   323 ANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGF 387
            |.||||.||..||||:.:...|.|..|.|||:|.||||:|:.|:|..|..||||||.|:||::||
 Frog   319 AEAQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAAINSTTSFFAGFVVFSVLGF 383

  Fly   388 LAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAIL 452
            :|.|..|.:.||.:.|.|||||.||:.||.:|.:|:||.|||.|||.|||||||..:|...|.|:
 Frog   384 MASEQGVHISKVAESGPGLAFIAYPKAVTLMPFAPIWAALFFFMLLILGLDSQFVGVEGFITGIM 448

  Fly   453 DRFPN-----LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLL-IAISECIL 511
            |.||.     :|: ::...|...:. :|..|...|..|||..||.|.|:|:...|| .|..||::
 Frog   449 DLFPQPINGFVRR-EVTAALCCLVC-FIIDLSMVTEGGMYVFQLFDYYSASGITLLWQAFWECVV 511

  Fly   512 IAWIYGSQRFLNDIQGMIGKR-----SWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYG-H 570
            |||:||:.||::||..|||.|     .|.|:        .:||...:.|..|:.|.|||..|. .
 Frog   512 IAWVYGADRFMDDIARMIGYRPLPYMKWCWS--------VLTPLVCVGIFVFHVVNYKPLTYNKS 568

  Fly   571 YVYPMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWG 624
            ||||.|.:|:||.:.|..:|.|.|....::.|:..||  |:| .||| .|..||
 Frog   569 YVYPWWGEAIGWSLALASMLCIPLTVVCKMLRSKGSL--RER-WHLL-TTPVWG 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..597	CDD:395155	245/553 (44%)
		Herpes_BLLF1	<884..1135	CDD:282904
slc6a8l	XP_012815966.1	SLC6sbd_CT1	61..654	CDD:271397	256/582 (44%)