DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlyT and si:ch211-132b12.1

DIOPT Version :9

Sequence 1:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster
Sequence 2:	NP_001076533.1	Gene:	si:ch211-132b12.1 / 100034467	ZFINID:	ZDB-GENE-050420-315	Length:	586	Species:	Danio rerio

Alignment Length:	547	Identity:	225/547 - (41%)
Similarity:	325/547 - (59%)	Gaps:	32/547 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 GESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMEL 115
            ||.| |||.|..:.:|||::.|..||||||||||||||..||||||||:.:.:|..|:||..:|:
Zfish     6 GEIE-ERGYWGSKMEFLLAVAGNVVGLGNVWRFPYLCYKYGGGAFLIPYLVFVVTCGVPLFLLEM 69

  Fly   116 SFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEP 180
            :.|||...|.|..:.|.|||..|:|.|..|:.....:||.:|:||.:||:..||...|||..|:.
Zfish    70 AMGQYTQQGGVTCWHRLCPLAEGIGYGGQLILLYSCMYYIVILAWALFYLIFSFKSQLPWATCDN 134

  Fly   181 AWSTKYCFSYAQADQCEATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSK 245
            .|:|..|.:..      ..|.|....:..|:|                 |.|.|::...||.||.
Zfish   135 TWNTDDCINLV------TKNLTINRTSLINST-----------------PAATEFWERRVLSLSG 176

  Fly   246 GIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTG 310
            |||:.|.|...:..||...|.|.:.|:.|||:|:||||||||.||||:|::|.:||:|||||..|
Zfish   177 GIEDIGKINWEILLCLIAMWIICYFCVWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQG 241

  Fly   311 ILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSF 375
            ::|||.|:..:||:.|||.:|..||.|:.|.:.|.:..|:||||:.||||:|.|.:...|..|||
Zfish   242 VVFYLYPEPARLADPQVWLEAGTQILFSYSVSVGSITVLASYNKYHNNCYRDCLGLCLLNSVTSF 306

  Fly   376 FAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQ 440
            .||..:|:::||:|.|..|.:|:|.:.|.|||||.||:.|..:|...:|||.||:|::.||||:|
Zfish   307 VAGFAVFTVLGFMAQEQGVPIEEVAESGPGLAFIAYPQAVAMMPFPQLWAVCFFIMIILLGLDTQ 371

  Fly   441 FALMETVTTAILDRFP-NLRQ--YKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVL 502
            |..||.|.|:::|.|| .||:  .:..::|...:..:.|.....|..|||..||.|.||.|.:.|
Zfish   372 FVSMEAVVTSVMDMFPVVLRREGRREILLLFFCLTCFFGQFIMVTEGGMYVFQLFDYYACNGTCL 436

  Fly   503 L-IAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPA 566
            | :::.|.:.:.||:|:.|..:.|:.|...|.   |:.:.:.|:|:||...|.....:.|||:|.
Zfish   437 LFLSVFESLTMGWIFGADRLFDIIEDMTKSRP---NYIFMLCWKYLTPLVSLVCFVCSMVEYQPL 498

  Fly   567 KYGH-YVYPMWADAVGWIVGLLPVLVI 592
            .:.. ||:|.||..:||::.|..::::
Zfish   499 TFNRWYVFPDWAYVLGWLLALSSIVLV 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyT	NP_611836.2	SNF	57..603	CDD:249680	221/541 (41%)
si:ch211-132b12.1	NP_001076533.1	SLC6sbd-TauT-like	11..549	CDD:271387	221/541 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820