Protein Alignment pippin and HXT5

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_011964.1
• Gene: HXT5 / 856496
• SGDID: S000001138
• Length: 592
• Species: Saccharomyces cerevisiae
• Alignment Length: 565
• Identity: 114/565 - (20%)
• Similarity: 212/565 - (37%)
• Gaps: 114/565 - (20%)

  Fly    14 PHTMSY-----QVVPGSEFQCKKASYSSR------KLSTIDEQDDDAANRRGMMHQILATCAVLL 67
            |.|..|     |..|.|       ||.|.      :|..:.::.|....::.....:..:...|:
Yeast    35 PGTAGYNDNLAQAKPVS-------SYISHEGPPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLM 92

  Fly    68 LSAGCGMPIGFSAILLPQLMDN------------NSTEIPIDVETGSWIASVHSLATPFGSLLSG 120
            ::.| |...|:....:...:..            |.|....||.||..: |:.::....|.::..
Yeast    93 VAFG-GFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMV-SIFNIGCAIGGIVLS 155

  Fly   121 PLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVI------------FARFLCGFATGILGGPG 173
            .|.|..||:           :|..|:.:..||.::|            ..|.:.|...|.:....
Yeast   156 KLGDMYGRK-----------IGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLA 209

  Fly   174 QVYIAETAEPNLRSLLIGAPYVAYSSGILMVY--SLGSMMYWRSVAWCANVLPL--------LSM 228
            .:.|:|.:...||..|:....:..:.||.:.|  :.|:..|..||.|   .:||        ..:
Yeast   210 PMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQW---RVPLGLCFAWSIFMI 271

  Fly   229 VSISFIPETPAWLLRNGHEKRALQALSFLRGSEISAQK-----ELNDMKQRLAKERVTTKTNENI 288
            |.::|:||:|.:|:..|..:.|.::|:  |.::.:...     |:.:.:..:..||:....:..
Yeast   272 VGMTFVPESPRYLVEVGKIEEAKRSLA--RANKTTEDSPLVTLEMENYQSSIEAERLAGSASWG- 333

  Fly   289 FQLCCQRVAIKP-----LVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRV 348
                 :.|..||     .::.::...||..:|.....:|...:....|.| ||.:.||...||..
Yeast   334 -----ELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLE-DSFETAIVLGVVNF 392

  Fly   349 ICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARF----------DQPKMSYDVFVGAG 403
            :........:....||..::...:|. :.|.|:    ||..          |||...     |||
Yeast   393 VSTFFSLYTVDRFGRRNCLLWGCVGM-ICCYVV----YASVGVTRLWPNGQDQPSSK-----GAG 447

  Fly   404 -CLLGY-----IIFNTALMVMPGIMIGELFPARIRGRTAGGVFASMNVALFIFAKKFPALQAMLK 462
             |::.:     ..|.|....:..::|.|.:|.|:||:......|...:..|:.:...|.:.:.:.
Yeast   448 NCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAIN 512

  Fly   463 MRGVFLVFGVSSFLLTAFMCLFQPETKGRSLEHIEDYFNGDNWLW 507
            ....::..|...|.. .::..|.|||||.:||.:.:.:..:...|
Yeast   513 FYYGYVFMGCMVFAY-FYVFFFVPETKGLTLEEVNEMYEENVLPW 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	101/495 (20%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	102/495 (21%)