Protein Alignment pippin and HXT4

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_011960.2
• Gene: HXT4 / 856492
• SGDID: S000001134
• Length: 576
• Species: Saccharomyces cerevisiae
• Alignment Length: 537
• Identity: 115/537 - (21%)
• Similarity: 211/537 - (39%)
• Gaps: 90/537 - (16%)

  Fly    33 SYSSRKLST------------IDEQDDDAAN------RRGMMHQILATCAVLLLSAG------CG 73
            |.|:..|||            .||..:::.|      :....:..::.|.:::...|      .|
Yeast    26 SDSNSALSTPSNKAERDDMKDFDENHEESNNYVEIPKKPASAYVTVSICCLMVAFGGFVFGWDTG 90

  Fly    74 MPIGFSA----ILLPQLMDNNSTEIPIDVETGSWIASVHSLATPFGSLLSGPLADYLGRRRTLIL 134
            ...||.|    |....:..::.|.....|.|| .|.|:.::....|.::...|.|..||:..||:
Yeast    91 TISGFVAQTDFIRRFGMKHHDGTYYLSKVRTG-LIVSIFNIGCAIGGIILAKLGDMYGRKMGLIV 154

  Fly   135 SVIPLLLGWSTLAIAKSIK--VVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAY 197
            .|:..::| ..:.||...|  .....|.:.|...|.:.....:.|:|.:..::|..|:....:..
Yeast   155 VVVIYIIG-IIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHIRGTLVSCYQLMI 218

  Fly   198 SSGILMVY--SLGSMMYWRSVAWCANVLPL-------LSMV-SISFIPETPAWLLRNG---HEKR 249
            :.||.:.|  :.|:..|..||.|   .:||       |.|: .::|:||:|.:|:..|   ..||
Yeast   219 TLGIFLGYCTNYGTKTYTNSVQW---RVPLGLGFAWALFMIGGMTFVPESPRYLVEVGKIEEAKR 280

  Fly   250 ALQALSFLRGSEISAQKELNDMKQRLAKERV----------TTKTNENIFQLCCQRVAIKPLVIV 304
            ::...:.:...:.:...|:..::..:..|::          :|||  .:||         .|::.
Yeast   281 SIALSNKVSADDPAVMAEVEVVQATVEAEKLAGNASWGEIFSTKT--KVFQ---------RLIMG 334

  Fly   305 IVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVRRRRIMIV 369
            .:...||..:|.....:|...:.:..|.| ||.:.:|...:|......|...::....|||.::
Yeast   335 AMIQSLQQLTGDNYFFYYGTTVFTAVGLE-DSFETSIVLGIVNFASTFVGIFLVERYGRRRCLL- 397

  Fly   370 SGIGSGLFCLVL--SVYQYARFDQPKMSYDVFVGAGCLLGY-----IIFNTALMVMPGIMIGELF 427
            .|..|...|:|:  ||.....:...|.:........|::.:     ..|.|....:|.::..|.|
Yeast   398 WGAASMTACMVVFASVGVTRLWPNGKKNGSSKGAGNCMIVFTCFYLFCFATTWAPIPFVVNSETF 462

  Fly   428 PARIRGRTAGGVFASMNVALFIFAKKFPALQAMLKMRGVFLVFG--VSSFLLTAFMCLFQPETKG 490
            |.|::.:......|...:..|:.....|.:...:.....::..|  |.|:....|   |.|||||
Yeast   463 PLRVKSKCMAIAQACNWIWGFLIGFFTPFISGAIDFYYGYVFMGCLVFSYFYVFF---FVPETKG 524

  Fly   491 RSLEHIEDYFNGDNWLW 507
            .:||.:       |.||
Yeast   525 LTLEEV-------NTLW 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	103/479 (22%)
HXT4	NP_011960.2	Sugar_tr	74..534	CDD:395036	105/487 (22%)