Protein Alignment pippin and VPS73

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 420
• Identity: 91/420 - (21%)
• Similarity: 183/420 - (43%)
• Gaps: 44/420 - (10%)

  Fly    94 IPIDVETGSWIASVHSLATPFGSLLSGPLADYLGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFA 158
            ||::.|....:.||..:....||..:..||:..||:.:.:::....::|...:..:.|.:.:|..
Yeast    84 IPLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNSNSYRGLIIG 148

  Fly   159 RFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMVYS----LGSMMYWRSVAWC 219
            |.|.|.:.|.|.....::|.|.|......||.....:....|:|:...    |.....||.:.:.
Yeast   149 RILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSYRWRWILFG 213

  Fly   220 ANVLPLLSMVSISFIPETPAWLLRNGHEKRALQALSFLRGSEI-SAQKELNDMKQRLAK-----E 278
            :.::.:|:......:.|:|.|||.:|....|..:|..|||... .|.:|:.|.:.::..     |
Yeast   214 SFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPLIE 278

  Fly   279 RVTTKT---NENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAA 340
            ..||.:   :.::::....|..:|...::.|....|.|.|...::.|...:||:.     ..|.|
Yeast   279 PTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLYGTKIISQL-----YPQHA 338

  Fly   341 IA----TAVVRVICCMVFCVVLIFVRRRRIMIVSGIGSGLFCLVLSVYQYARFDQPKMSYDV--- 398
            |.    .::|.|:..::..:::..:.|:.:::.|.:...:...::.:    ..:..||:..:
Yeast   339 IRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGI----AMNHNKMNLLIVFS 399

  Fly   399 FVGAGCLLGYIIFNTALMVMPGIMIGELFPAR--IRGRTAGGVFASMN-VALFIFAKKFPALQAM 460
            |:..|      :|...|..:|.|::.|:...:  :..:..|.:   .| |..||.|..||.:..:
Yeast   400 FIYMG------VFTMGLNPLPFIIMREVSKPQDMVLAQRYGTI---CNWVGTFIIAYTFPIIHDV 455

  Fly   461 LKMRG-VFLVFGVSSFLLTAFMCLFQPETK 489
            |.  | ||::|.:.:..::||:....||||
Yeast   456 LS--GYVFIIFAIIACSISAFIWKKVPETK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	91/420 (22%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	91/420 (22%)