DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and STL1

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_010825.3	Gene:	STL1 / 852149	SGDID:	S000002944	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	475	Identity:	100/475 - (21%)
Similarity:	178/475 - (37%)	Gaps:	80/475 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 GFSAILLPQLMDNN--STEIPIDVETGSW----------IASVHSLATPFGSLLSGPLADYLGRR 129
            |:...|:..|:...  :.|.|...|.|..          ..|.:.|....|||......:.:||:
Yeast    43 GYDQGLMASLITGKQFNYEFPATKENGDHDRHATVVQGATTSCYELGCFAGSLFVMFCGERIGRK 107

  Fly   130 RTLILSVIPLLLG--WSTLAIAK--SIKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLI 190
            ..:::..:..::|  .||.|...  ::...|..|.:.|..||:......|:.:|.::...|.||:
Yeast   108 PLILMGSVITIIGAVISTCAFRGYWALGQFIIGRVVTGVGTGLNTSTIPVWQSEMSKAENRGLLV 172

  Fly   191 GAPYVAYSSGILMVYSL-------GSMMYWRSVAWCANVLPLLSMVSISFIPETPAWLLRNGHEK 248
            .......:.|.::.|.:       .|.:.||.......|..|..:..:..:||:|.||:.....:
Yeast   173 NLEGSTIAFGTMIAYWIDFGLSYTNSSVQWRFPVSMQIVFALFLLAFMIKLPESPRWLISQSRTE 237

  Fly   249 RALQALSFLRGSE------ISAQKELNDMKQRLAKERVTTKT------NENIFQLCCQRVAIKPL 301
            .|...:..|..::      |:....|:|...|...|:.:..:      ::|:     ||.
Yeast   238 EARYLVGTLDDADPNDEEVITEVAMLHDAVNRTKHEKHSLSSLFSRGRSQNL-----QRA----- 292

  Fly   302 VIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVVLIFVR---R 363
            :|.......|.|:|....|:|:..:.:: ..:.|.:.:.|...|...|..:........:.   |
Yeast   293 LIAASTQFFQQFTGCNAAIYYSTVLFNK-TIKLDYRLSMIIGGVFATIYALSTIGSFFLIEKLGR 356

  Fly   364 RRIMIVSGIGSGL------FCLVLSVYQYARFDQPKMSYDVFVGA--GCLLGYIIFNTALMVMPG 420
            |::.::...|..:      .|||....:.||            ||  |..|....|..:|:.:|.
Yeast   357 RKLFLLGATGQAVSFTITFACLVKENKENAR------------GAAVGLFLFITFFGLSLLSLPW 409

  Fly   421 IMIGELFPARIRGRTAGGVFAS-----MNVALFIFAKKFPALQAMLKMRGVFLVFGVSSFLLTAF 480
            |...|:...::|..|  ..|::     .|.|:.:|...|......    |.:|.|.|.::|....
Yeast   410 IYPPEIASMKVRAST--NAFSTCTNWLCNFAVVMFTPIFIGQSGW----GCYLFFAVMNYLYIPV 468

  Fly   481 MCLFQPETKGRSLEHIEDYF 500
            :..|.|||.|||||.|:..|
Yeast   469 IFFFYPETAGRSLEEIDIIF 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	89/457 (19%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	95/458 (21%)
STL1	NP_010825.3	Sugar_tr	32..488	CDD:395036	99/473 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810