DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4797 and INT3

DIOPT Version :9

Sequence 1:	NP_726368.2	Gene:	CG4797 / 37770	FlyBaseID:	FBgn0034909	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_181117.1	Gene:	INT3 / 818146	AraportID:	AT2G35740	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	565	Identity:	129/565 - (22%)
Similarity:	226/565 - (40%)	Gaps:	132/565 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 LLLSAGC-GMPIGFSAILLPQLMDNNSTEIPIDVETGSWIASVHSLATPFGSLLSGPLA----DY 125
            |.||||. |:..|::..::...:.....|.. :|:..:|:..:....|..|:::...:.    |.
plant    29 LALSAGIGGLLFGYNTGVIAGALLYIKEEFG-EVDNKTWLQEIIVSMTVAGAIVGAAIGGWYNDK 92

  Fly   126 LGRRRTLILSVIPLLLGWSTLAIAKSIKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLI 190
            .|||.:::::.:..|||...:.||.:..|:|..|.|.||..|:......:||:|.:...:|..|:
plant    93 FGRRMSVLIADVLFLLGALVMVIAHAPWVIILGRLLVGFGVGMASMTSPLYISEMSPARIRGALV 157

  Fly   191 --------GAPYVAYSSGILMVYSLGSMMYWRSVAWCANVLPLLSMVSISF---IPETPAWLLRN 244
                    |..:::|...:..|::.|:   ||   |...|..:.:::....   :||:|.||.||
plant   158 STNGLLITGGQFLSYLINLAFVHTPGT---WR---WMLGVSAIPAIIQFCLMLTLPESPRWLYRN 216

  Fly   245 GHEKRALQAL-----SFLRGSEISAQKELNDMKQRLAKERVTTKT-NENIFQLCCQRVAIKPLVI 303
            ..:..:...|     :.:..:||:|.||  .::...|.|.:...| ::.:.......|....|..
plant   217 DRKAESRDILERIYPAEMVEAEIAALKE--SVRAETADEDIIGHTFSDKLRGALSNPVVRHGLAA 279

  Fly   304 VIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQAAIATAVVRVICCMVFCVV-LIFV---RRR 364
            .|...:.|.|.|...|::|:..::...|  :.|.:.|:|.|::......|..|| ::||   .||
plant   280 GITVQVAQQFVGINTVMYYSPTILQFAG--YASNKTAMALALITSGLNAVGSVVSMMFVDRYGRR 342

  Fly   365 RIMIVSGIGSGLFCLVL--SVYQYARFDQPK---------------------------------- 393
            ::||:|..|. :.|||:  :|:..|....||
plant   343 KLMIISMFGI-ITCLVILAAVFNEASNHAPKIDKRDSRNFAKNATCPAFAPFTASRSPPSNWNCM 406

  Fly   394 --MSYD--------------------------------VFVGAGC--LLGY----------IIFN 412
              :.||                                .|...||  ..||          |::.
plant   407 KCLQYDCGFCSNGAQEYAPGACIVQSADMKALCHSKGRTFFKDGCPSKFGYLAIVFLGLYIIVYA 471

  Fly   413 TALMVMPGIMIGELFPARIRGRTAGGVFASMN-VALFIFAKKFPALQAMLKMRGVFLVFGVSSFL 476
            ..:..:|.|:..|::|.|.|| .|||:.|..| ::..:.::.|..|...:...|.||:|..||.:
plant   472 PGMGTVPWIVNSEIYPLRYRG-LAGGIAAVSNWMSNLVVSETFLTLTNAVGSSGTFLLFAGSSAV 535

  Fly   477 LTAFMCLFQPETKGRSLEHIEDYFNGDNWLWFRRDRGYKTVNLQP 521
            ...|:.|..|||||...|.:|....|          |::...|:|
plant   536 GLFFIWLLVPETKGLQFEEVEKLLEG----------GFRPSLLRP 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4797	NP_726368.2	MFS	64..484	CDD:119392	117/526 (22%)
CG4797	NP_726368.2	Sugar_tr	89..497	CDD:278511	117/515 (23%)
INT3	NP_181117.1	SP	1..555	CDD:273317	124/538 (23%)
INT3	NP_181117.1	MFS	31..>364	CDD:119392	84/344 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810