Protein Alignment pippin and SLC2A11

DIOPT Version :10

• Sequence 1: NP_726368.2
• Gene: pippin / 37770
• FlyBaseID: FBgn0034909
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_001269793.1
• Gene: SLC2A11 / 66035
• HGNCID: 14239
• Length: 535
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 187/459 - (40%)
• Gaps: 58/459 - (12%)

  Fly    43 DEQDDDAANRRGMMHQILATCAVLLLSAGCGMPIGF----SAILLPQLMDNNSTEIPIDVETG-- 101
            ||.:.....|..:..:||   .:.:.:||.|....|    |.|..|.|.....|.......||
Human     3 DELEPSLRPRTQIQGRIL---LLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEP 64

  Fly   102 ----------SWIASVHSLATPFGSLLSGPLADYLGRRRTLILSVI-----PLLLGWSTLAIAKS 151
                      |.|.|::.|...||:||:||||..|||:::|:::.|     .:|.|:|..  |.|
Human    65 LPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRK--AGS 127

  Fly   152 IKVVIFARFLCGFATGILGGPGQVYIAETAEPNLRSLLIGAPYVAYSSGILMVY------SLGSM 210
            .::::..|.|.|...|:......:|:.|:|...||..:..:..:..:.||:|..      .||..
Human   128 FEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGP 192

  Fly   211 MYWRSVAWCANVLPLLSMVSISFIPETPAWLLRN-GHEKRALQALSFLRGSEISAQKELNDM-KQ 273
            ..|..:.....|...|.:.|:..:||:|.:||.: |..:..|.||..||||...| .||.:: ::
Human   193 QAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLA-GELEELEEE 256

  Fly   274 RLAKERVTTKTNENIFQLCCQRVAIKPLVIVIVFSLLQMFSGTFIVIFYAVDMISEFGAEFDSKQ 338
            |.|.:....:....:||   .|...:.:..::|........|...|..||..:..:.|.    .:
Human   257 RAACQGCRARRPWELFQ---HRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGV----PE 314

  Fly   339 AAIATAVVRVICCMVFCVVLIFVRRRRIMIVSGI--GSGLFCLVLSVYQYARFDQPKMSYDVFVG 401
            |.|..|::....|.:...|         :.|:|:  |.|:...:.|.....|..|....:.:::.
Human   315 AKIQYAIIGTGSCELLTAV---------VSVAGVDEGWGVQAGLTSTSPPPRPRQSSFPWTLYLA 370

  Fly   402 AGCLLGYII-FNTALMVMPGIMIGELFPARIRGRTAGGVFASMNVALFIFAKKFPALQAMLKMRG 465
            ..|:..:|: |......:.||:..|||....|........|.|.:.|.:....||.:..:    |
Human   371 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMVL----G 431

  Fly   466 VFLV 469
            .||:
Human   432 SFLI 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pippin	NP_726368.2	MFS_GLUT6_8_Class3_like	59..495	CDD:340916	109/443 (25%)
SLC2A11	NP_001269793.1	MFS	23..433	CDD:475125	105/432 (24%)